PPAP2A and FAHD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PPAP2A	FAHD1
Gene Name		phosphatidic acid phosphatase type 2A	fumarylacetoacetate hydrolase domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol
	Molecular Function	Phosphatidate Phosphatase Activity	Acetylpyruvate Hydrolase Activity Fumarylpyruvate Hydrolase Activity Metal Ion Binding Acylpyruvate Hydrolase Activity
	Biological Process	Protein Dephosphorylation Lipid Metabolic Process Sphingolipid Metabolic Process Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Germ Cell Migration Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Small Molecule Metabolic Process Phospholipid Dephosphorylation	Metabolic Process
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: FAHD1 FXYD1	3 interactors: EXOSC4 PAXIP1 PPAP2A
Entrez ID		8611	81889
HPRD ID		06178	13286
Ensembl ID		ENSG00000067113	ENSG00000180185
Uniprot IDs		O14494	Q6P587
PDB IDs			1SAW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sodium Ion Export From Cell Regulation Of Cardiac Muscle Cell Membrane Potential Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Regulation Of Sodium Ion Transport Positive Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport Chloride Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Heart Contraction	Positive Regulation Of Histone H3-K36 Methylation Nuclear MRNA Surveillance RNA Surveillance Chorion Development DNA Deamination Histone MRNA Catabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of DNA-templated Transcription, Initiation Maturation Of 5.8S RRNA Germ Cell Migration Histone MRNA Metabolic Process Positive Regulation Of Histone Acetylation Regulation Of DNA-templated Transcription, Initiation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cell Migration RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Histone H3-K4 Methylation Regulation Of Isotype Switching Cell Motility Positive Regulation Of Immunoglobulin Mediated Immune Response Adipose Tissue Development Positive Regulation Of Histone Methylation Positive Regulation Of Immunoglobulin Production Phospholipid Dephosphorylation Androgen Receptor Signaling Pathway DNA Metabolic Process Regulation Of Histone Acetylation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Histone Methylation Locomotion Regulation Of DNA Recombination Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Histone Modification Positive Regulation Of B Cell Activation Sphingolipid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Endothelial Cell Migration DNA Modification Movement Of Cell Or Subcellular Component Histone Lysine Methylation Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Vasculogenesis
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