SERPINB8 and CAP1

Number of citations of the paper that reports this interaction (PMID 8761950)
6

Data Source:
HPRD (in vivo, two hybrid)

		SERPINB8	CAP1
Gene Name		serpin peptidase inhibitor, clade B (ovalbumin), member 8	CAP, adenylate cyclase-associated protein 1 (yeast)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytosol Extracellular Vesicular Exosome	Plasma Membrane Focal Adhesion Cortical Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Actin Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Ameboidal-type Cell Migration Platelet Degranulation Receptor-mediated Endocytosis Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity Axon Guidance Blood Coagulation Actin Cytoskeleton Organization Platelet Activation
Pathways		Dissolution of Fibrin Clot	Role of Abl in Robo-Slit signaling Axon guidance Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Signaling by Robo receptor
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)
Protein-Protein Interactions		5 interactors: CAP1 F10 F2 FURIN PRSS1	9 interactors: ACTB ACTG1 BARD1 CAP2 LIG4 MYOC PLA2G4A SERPINB8 UCHL5
Entrez ID		5271	10487
HPRD ID		03412	09869
Ensembl ID		ENSG00000166401	ENSG00000131236
Uniprot IDs		B4DTW2 P50452	D3DPU2 Q01518
PDB IDs			1K8F
Enriched GO Terms of Interacting Partners?		Peptidyl-glutamic Acid Carboxylation Blood Coagulation, Intrinsic Pathway Post-translational Protein Modification Blood Coagulation Hemostasis Proteolysis Regulation Of Body Fluid Levels Extracellular Matrix Disassembly Wound Healing Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Proteolysis Response To Wounding Nerve Growth Factor Production Protein Activation Cascade Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Peptidyl-amino Acid Modification Platelet Activation Protein Metabolic Process Negative Regulation Of Cytokine Production Nerve Growth Factor Processing Blood Coagulation, Extrinsic Pathway Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Production Cellular Protein Modification Process Negative Regulation Of Fibrinolysis Negative Regulation Of Proteolysis Viral Protein Processing Negative Regulation Of Protein Processing Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Fibrinolysis Regulation Of Protein Processing Toll Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Platelet Activation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cobalamin Metabolic Process Signal Peptide Processing Secretion By Cell Cellular Protein Metabolic Process Virion Assembly Regulation Of Cytokine Production Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Metabolic Process Activation Of Adenylate Cyclase Activity Regulation Of Astrocyte Differentiation	Tissue Homeostasis Platelet Activation Nervous System Development Cell Activation Multicellular Organismal Homeostasis Platelet Aggregation Generation Of Neurons Neuron Projection Development Neurogenesis Homotypic Cell-cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Retina Homeostasis Cellular Response To Stimulus Cell Development Neuron Development Axon Guidance ERBB2-ERBB3 Signaling Pathway DNA Ligation Involved In DNA Recombination Skeletal Muscle Hypertrophy Blood Coagulation Hemostasis Midbrain Development Adherens Junction Organization Neuron Differentiation Response To Stress Cell Projection Organization Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB2 Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Single Organismal Cell-cell Adhesion Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation DNA Repair Wound Healing Chemotaxis Response To Stimulus Neuron Projection Morphogenesis Platelet Activating Factor Biosynthetic Process System Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Platelet Activating Factor Metabolic Process Response To Wounding Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Process
Tagcloud ?		attracted botulinum c3 candidates decades dialysis disappointing displaying disturbance dominated epigenome finger h3k9me3 immunological mononuclear myh3 myosin nephrology nog noggin pcgf2 peptidase polycomb quantified rac3 seq throughput uremia	alarco albicans balan brefeldin bzip caglr1 cai4 catrr1 caycf1 cdr1 cdr2 cerulenin cjd21 diamide facilitator fcz flr1 fr2 hyperactive hyperresistant mainville mdr1 nitroquinoline phenanthroline raymond reintroduction talibi transformants yap1
Tagcloud (Difference) ?		attracted botulinum c3 candidates decades dialysis disappointing displaying disturbance dominated epigenome finger h3k9me3 immunological mononuclear myh3 myosin nephrology nog noggin pcgf2 peptidase polycomb quantified rac3 seq throughput uremia	alarco albicans balan brefeldin bzip caglr1 cai4 catrr1 caycf1 cdr1 cdr2 cerulenin cjd21 diamide facilitator fcz flr1 fr2 hyperactive hyperresistant mainville mdr1 nitroquinoline phenanthroline raymond reintroduction talibi transformants yap1
Tagcloud (Intersection) ?