SERPINB8

Description		serpin family B member 8
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Extracellular Matrix Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity Epithelial Cell-cell Adhesion
Pathways		Dissolution of Fibrin Clot
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)
Interacting Genes		5 interacting genes: CAP1 F10 F2 FURIN PRSS1
Entrez ID		5271
HPRD ID		03412
Ensembl ID		ENSG00000166401
Uniprot IDs		A0A1B0GU38 P50452
PDB IDs
Enriched GO Terms of Interacting Partners?		Serine-type Peptidase Activity Serine-type Endopeptidase Activity Golgi Lumen Peptidase Activity Extracellular Region Extracellular Matrix Disassembly Proteolysis Endopeptidase Activity Extracellular Space Negative Regulation Of Nerve Growth Factor Production Dibasic Protein Processing Zymogen Inhibition Hydrolase Activity Coagulation Blood Coagulation Hemostasis Blood Microparticle Golgi Apparatus Subcompartment Regulation Of Nerve Growth Factor Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Nerve Growth Factor Production Negative Regulation Of Neurotrophin Production Negative Regulation Of Proteolysis Heparin Binding Negative Regulation Of Receptor Catabolic Process Thrombospondin Receptor Activity Viral Translation Viral Life Cycle CAMP-mediated Signaling Neutrophil-mediated Killing Of Gram-negative Bacterium Cytokine Precursor Processing Nerve Growth Factor Binding Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Heparan Sulfate Binding Regulation Of Body Fluid Levels Signal Peptide Processing Endoplasmic Reticulum Lumen Thrombin-activated Receptor Signaling Pathway Neutrophil-mediated Killing Of Bacterium Cytolysis By Host Of Symbiont Cells Negative Regulation Of Fibrinolysis Negative Regulation Of Transforming Growth Factor Beta Production Adenylate Cyclase Binding Modification Of Postsynaptic Actin Cytoskeleton Protein Metabolic Process Negative Regulation Of Cytokine Production
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