SLC25A3 and MX1

Number of citations: 0 (PubMedID 25447205)
Data Source: BioGRID (two hybrid)

		SLC25A3	MX1
Name		solute carrier family 25 member 3	MX dynamin like GTPase 1
Structure		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane Extracellular Exosome	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Microtubule Plasma Membrane Membrane Nuclear Membrane Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Phosphate Transmembrane Transporter Activity Protein Binding Symporter Activity Phosphate:proton Symporter Activity Protein-containing Complex Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Phosphate Ion Transmembrane Transport Proton Transmembrane Transport Mitochondrial Phosphate Ion Transmembrane Transport	Immune System Process Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		None	ISG15 antiviral mechanism Interferon alpha/beta signaling
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		1 novel interactors: IFT57	13 novel interactors: CCL16 CD5 DCP2 GGPS1 GPC4 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PRDX6 PSG9 ZFP36
Interacting Genes		6 interacting genes: DUX4 MBD1 MX1 PTEN RHBDD2 YWHAG	42 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA FXR1 GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623
Entrez ID		5250	4599
HPRD ID		02654	00919
Ensembl ID		ENSG00000075415	ENSG00000157601
Uniprot IDs		A0A024RBE8 A0A024RBH9 Q00325	H9KVC7 P20591
PDB IDs		Not available	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
GO Terms Enriched among Interactors		None	Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding Cation Channel Complex PML Body Regulation Of Cytosolic Calcium Ion Concentration Calcium Channel Activity Transcription Corepressor Activity Cytoplasmic Ribonucleoprotein Granule SUMO Ligase Activity Actinin Binding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Monoatomic Ion Channel Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Calcium Ion Homeostasis SUMO Transferase Activity Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Calcium Ion Transport Regulation Of Cytokine Production Involved In Inflammatory Response Nucleus Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Regulation Of T Cell Activation Identical Protein Binding Regulation Of T Cell Differentiation Intracellular Monoatomic Cation Homeostasis Associative Learning Inorganic Ion Homeostasis Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Protein Homodimerization Activity Intracellular Monoatomic Ion Homeostasis Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Envelope Lumen SUMO Binding Synapse Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing