EPHB1

Gene Name		EPH receptor B1
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Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Early Endosome Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity
	Biological Process	Angiogenesis Axon Guidance Peptidyl-tyrosine Phosphorylation Optic Nerve Morphogenesis Central Nervous System Projection Neuron Axonogenesis Neurogenesis Establishment Of Cell Polarity Retinal Ganglion Cell Axon Guidance Cell-substrate Adhesion Regulation Of JNK Cascade Protein Autophosphorylation Ephrin Receptor Signaling Pathway Camera-type Eye Morphogenesis Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Positive Regulation Of Synapse Assembly Cell Chemotaxis Dendritic Spine Development Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Regulation Of Neuron Death
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-protein Interactions		11 interactors: ACP1 EFNA1 EFNA5 EFNB1 EFNB2 EPHB6 GRB10 GRB2 NCK1 PRKCG PXN
Entrez ID		2047
HPRD ID		02790
Ensembl ID		ENSG00000154928
Uniprot IDs		P54762
PDB IDs		2DJS 2EAO
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axon Guidance Cell Morphogenesis Involved In Differentiation Ephrin Receptor Signaling Pathway Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Neuron Projection Development Cell Surface Receptor Signaling Pathway Cell Projection Morphogenesis Cell Part Morphogenesis Movement Of Cell Or Subcellular Component Neuron Development Neuron Differentiation Cell Development Locomotion Nervous System Development Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Signal Transduction Response To External Stimulus Regulation Of Cell Adhesion Signaling Cell Communication Regulation Of Phosphorylation Regulation Of Cell-cell Adhesion Signal Complex Assembly Multicellular Organismal Development Cell Differentiation Regulation Of Phosphorus Metabolic Process Cell Migration Cellular Response To Stimulus Anatomical Structure Development Cell Motility Cell-cell Signaling Positive Regulation Of Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Developmental Process System Development Positive Regulation Of T Cell Activation Cell Adhesion Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Signal Transduction
Tagcloud ?		anlage b3 cascades cortical cue endogenously entering ephrin fak gives interneurons migrate migrating misrouted path pfak poa preoptic psrc repulsion repulsive reverse stop str striatal striatum superficial terminate