PEX13 and CEP19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PEX13	CEP19
Description		peroxisomal biogenesis factor 13	centrosomal protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol Membrane Peroxisomal Importomer Complex	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity	Protein Binding
	Biological Process	Fatty Acid Alpha-oxidation Neuron Migration Suckling Behavior Protein Monoubiquitination Locomotory Behavior Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Receptor Recycling Cerebral Cortex Cell Migration Cellular Response To Reactive Oxygen Species Protein Unfolding Protein Import Into Peroxisome Matrix, Substrate Release Microtubule-based Peroxisome Localization	Cell Projection Organization Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Crohn's disease ( 22412388) Erectile dysfunction ( 30583798)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851)
Interacting Genes		6 interacting genes: CEP19 PEX19 PEX5 PEX7 PRRG4 SPRR2A	47 interacting genes: AK4 ANAPC15 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PGCKA1 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81
Entrez ID		5194	84984
HPRD ID		03475	17488
Ensembl ID		ENSG00000162928	ENSG00000174007
Uniprot IDs		Q92968	A8MX07 Q96LK0
PDB IDs		7Z0I 7Z0J 7Z0K
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Peroxisome Membrane Targeting Sequence Binding Peroxisomal Membrane Protein Import Into Peroxisome Membrane Protein Carrier Chaperone Peroxisome Protein Import Into Peroxisome Matrix Protein Targeting Intracellular Protein Transmembrane Transport Peroxisomal Matrix Fatty Acid Beta-oxidation Establishment Of Protein Localization To Organelle Fatty Acid Catabolic Process Protein Transmembrane Transport Fatty Acid Oxidation Peroxisome Matrix Targeting Signal-2 Binding Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment Lipid Oxidation Intracellular Protein Transport Peroxisome Matrix Targeting Signal-1 Binding Lipid Modification Neuron Migration Protein Localization To Organelle Peroxisome Membrane Biogenesis Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Vesicle Targeting, To, From Or Within Golgi Establishment Of Protein Localization To Membrane Protein Import Into Peroxisome Matrix, Substrate Release Carboxylic Acid Catabolic Process Membrane Biogenesis Host-mediated Modulation Of Intestinal Microbiota Composition Lipid Catabolic Process Protein Import Into Peroxisome Matrix, Receptor Recycling Peroxisome Fission Microtubule Anchoring At Centrosome Protein Transport Fatty Acid Metabolic Process Ether Lipid Biosynthetic Process Protein Unfolding Protein Localization To Membrane Microtubule Anchoring At Microtubule Organizing Center Organelle Organization Intracellular Transport
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