PEX13

Description		peroxisomal biogenesis factor 13
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GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol Membrane Peroxisomal Importomer Complex
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Fatty Acid Alpha-oxidation Neuron Migration Suckling Behavior Protein Monoubiquitination Locomotory Behavior Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Receptor Recycling Cerebral Cortex Cell Migration Cellular Response To Reactive Oxygen Species Protein Unfolding Protein Import Into Peroxisome Matrix, Substrate Release Microtubule-based Peroxisome Localization
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Crohn's disease ( 22412388) Erectile dysfunction ( 30583798)
Interacting Genes		6 interacting genes: CEP19 PEX19 PEX5 PEX7 PRRG4 SPRR2A
Entrez ID		5194
HPRD ID		03475
Ensembl ID		ENSG00000162928
Uniprot IDs		Q92968
PDB IDs		7Z0I 7Z0J 7Z0K
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Peroxisome Membrane Targeting Sequence Binding Peroxisomal Membrane Protein Import Into Peroxisome Membrane Protein Carrier Chaperone Peroxisome Protein Import Into Peroxisome Matrix Protein Targeting Intracellular Protein Transmembrane Transport Peroxisomal Matrix Fatty Acid Beta-oxidation Establishment Of Protein Localization To Organelle Fatty Acid Catabolic Process Protein Transmembrane Transport Fatty Acid Oxidation Peroxisome Matrix Targeting Signal-2 Binding Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment Lipid Oxidation Intracellular Protein Transport Peroxisome Matrix Targeting Signal-1 Binding Lipid Modification Neuron Migration Protein Localization To Organelle Peroxisome Membrane Biogenesis Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Vesicle Targeting, To, From Or Within Golgi Establishment Of Protein Localization To Membrane Protein Import Into Peroxisome Matrix, Substrate Release Carboxylic Acid Catabolic Process Membrane Biogenesis Host-mediated Modulation Of Intestinal Microbiota Composition Lipid Catabolic Process Protein Import Into Peroxisome Matrix, Receptor Recycling Peroxisome Fission Microtubule Anchoring At Centrosome Protein Transport Fatty Acid Metabolic Process Ether Lipid Biosynthetic Process Protein Unfolding Protein Localization To Membrane Microtubule Anchoring At Microtubule Organizing Center Organelle Organization Intracellular Transport
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