MYOZ2 and PPP3CB

Number of citations of the paper that reports this interaction (PMID 11114196)
50

Data Source:
HPRD (in vivo)

		MYOZ2	PPP3CB
Gene Name		myozenin 2	protein phosphatase 3, catalytic subunit, beta isozyme
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Actin Cytoskeleton Sarcomere Z Disc	Nucleoplasm Cytosol Plasma Membrane Calcineurin Complex Z Disc T-tubule
	Molecular Function	Actin Binding Protein Binding Protein Phosphatase 2B Binding Telethonin Binding	Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Drug Binding Enzyme Binding Protein Phosphatase 2B Binding Calmodulin-dependent Protein Phosphatase Activity Protein Dimerization Activity
	Biological Process	Biological_process	Negative Regulation Of T Cell Mediated Cytotoxicity Protein Phosphorylation Protein Dephosphorylation Signal Transduction Heart Development Learning Memory Dephosphorylation Calcium Ion-dependent Exocytosis T Cell Differentiation Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade Response To Cytokine Social Behavior Cellular Response To Drug Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Fc-epsilon Receptor Signaling Pathway T Cell Proliferation T Cell Activation T Cell Homeostasis Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Synaptic Plasticity Axon Extension Regulation Of Insulin Secretion Positive Regulation Of NFAT Protein Import Into Nucleus
Pathways			Signaling by GPCR Ca2+ pathway Opioid Signalling DARPP-32 events Fc epsilon receptor (FCERI) signaling FCERI mediated Ca+2 mobilization Signaling by Wnt Innate Immune System beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ACTN1 ACTN2 ACTN4 DRICH1 EWSR1 FLNC LDB3 MYB PPP3CA PPP3CB RBPMS ZDHHC17	12 interactors: CABIN1 IRAK1 IRF2 JUN MARCH7 MYOZ2 MYOZ3 NFATC2 SLC8A1 SLC8A2 SLC8A3 SOCS3
Entrez ID		51778	5532
HPRD ID		05724	00235
Ensembl ID		ENSG00000172399	ENSG00000107758
Uniprot IDs		Q9NPC6	P16298
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Cell Activation Cell Junction Assembly Calcineurin-NFAT Signaling Cascade Protein Localization To Cell Junction Platelet Degranulation Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transport Exocytosis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Inositol Phosphate-mediated Signaling Actin Crosslink Formation Blood Coagulation Hemostasis Striated Muscle Cell Development Positive Regulation Of Intracellular Protein Transport Muscle Cell Development Regulation Of Protein Import Into Nucleus Secretion By Cell Platelet Activation Regulation Of Protein Localization To Nucleus Focal Adhesion Assembly Regulation Of Body Fluid Levels Cell-cell Junction Organization Regulation Of Nucleocytoplasmic Transport Wound Healing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Striated Muscle Cell Differentiation Regulation Of RNA Metabolic Process Secretion Actin Filament-based Process Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Intracellular Transport Tight Junction Assembly Regulation Of Intracellular Protein Transport Response To Wounding Adherens Junction Assembly Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Cellular Response To Drug Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transporter Activity Regulation Of Protein Localization Muscle Cell Differentiation Actin Filament Bundle Assembly Positive Regulation Of Protein Transport	Calcium Ion Export Response To Wounding Innate Immune Response Response To Organonitrogen Compound Response To Stress Blood Coagulation Hemostasis Response To Purine-containing Compound Cellular Response To Organic Substance Cell Communication Sodium Ion Transmembrane Transport Regulation Of Body Fluid Levels Calcium Ion Import Calcium Ion Transmembrane Transport Wound Healing Immune Response Regulation Of Innate Immune Response Immune System Process Sodium Ion Transport Defense Response Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Response To Cytokine Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Positive Regulation Of Smooth Muscle Cell Proliferation Toll-like Receptor TLR1:TLR2 Signaling Pathway Calcium Ion Transport Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Response To Organic Substance MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Immune Response Cellular Response To Potassium Ion Starvation MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Calcium Ion Import Into Cell Calcium Ion Export From Cell Leading Edge Cell Differentiation Sodium Ion Import Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cytokine-mediated Signaling Pathway Regulation Of Smooth Muscle Cell Proliferation Immune Response-regulating Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Type I Interferon
Tagcloud ?		actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myozenin nfatc pp2b ppp3cb quantifying rcan1 s48p transgene unsettled	actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myoz2 myozenin nfatc pp2b quantifying rcan1 s48p transgene unsettled
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myoz2 myozenin nfatc pp2b ppp3cb quantifying rcan1 s48p transgene unsettled