POLR3K and CENPP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLR3K	CENPP
Description		RNA polymerase III subunit K	centromere protein P
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	Nucleic Acid Binding DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Immune System Process DNA-templated Transcription Transcription By RNA Polymerase III Innate Immune Response Defense Response To Virus	Chromosome Segregation CENP-A Containing Chromatin Assembly
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)	End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: CENPP SDCBP TRIM69	26 interacting genes: AKAP19 ATP6V0D2 BACH2 CCDC33 CCDC85B CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765
Entrez ID		51728	401541
HPRD ID		16187	17989
Ensembl ID		ENSG00000161980	ENSG00000188312
Uniprot IDs		Q9Y2Y1	Q6IPU0
PDB IDs		7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Regulation Of Extracellular Exosome Assembly	Centrosome Cycle
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