LSM7 and SART3

Number of citations of the paper that reports this interaction (PMID 19615732)
279

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology)

		LSM7	SART3
Gene Name		LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	squamous cell carcinoma antigen recognized by T cells 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytosol	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	Protein Binding U6 SnRNA Binding	Nucleotide Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Poly(A) RNA Binding Ubiquitin-specific Protease Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly Regulation Of Gene Expression Homeostasis Of Number Of Cells Hematopoietic Stem Cell Proliferation Positive Regulation Of Histone Deubiquitination
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF TACC1 ZSCAN26	12 interactors: AR C6 COIL HIST2H2AC HIST2H2BE KPNA2 LSM7 MEGF10 PRPF3 RNPS1 USP15 USP4
Entrez ID		51690	9733
HPRD ID		06287	11532
Ensembl ID		ENSG00000130332	ENSG00000075856
Uniprot IDs		Q9UK45	B7ZKM0 Q15020
PDB IDs			2DO4
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Nuclear-transcribed MRNA Catabolic Process RNA Processing MRNA Catabolic Process RNA Catabolic Process MRNA Splicing, Via Spliceosome Aromatic Compound Catabolic Process RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Gene Expression Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Histone MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process NcRNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Catabolic Process RRNA Processing RRNA Metabolic Process Termination Of RNA Polymerase II Transcription Ribosome Biogenesis Histone H3-K4 Acetylation Positive Regulation Of Histone Deubiquitination Notochord Cell Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Positive Regulation Of Hemoglobin Biosynthetic Process Cellular Metabolic Process DNA-templated Transcription, Termination Metabolic Process MRNA 3'-end Processing Cellular Macromolecular Complex Assembly Axial Mesoderm Formation Retrograde Transport, Plasma Membrane To Golgi RNA 3'-end Processing Regulation Of Hemoglobin Biosynthetic Process Notochord Formation Regulation Of Protein Deubiquitination Lens Fiber Cell Morphogenesis Axial Mesoderm Morphogenesis Regulation Of Protein Localization	RNA Splicing Spliceosomal Tri-snRNP Complex Assembly MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Negative Regulation Of Integrin Biosynthetic Process Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Cell Proliferation Histone H2B Conserved C-terminal Lysine Deubiquitination Skeletal Muscle Satellite Cell Activation Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Integrin Biosynthetic Process Positive Regulation Of Activation Of Membrane Attack Complex Regulation Of Integrin Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Skeletal Muscle Satellite Cell Differentiation RNA Catabolic Process Recognition Of Apoptotic Cell Regulation Of Proteasomal Protein Catabolic Process Monoubiquitinated Protein Deubiquitination Positive Regulation Of Transcription From RNA Polymerase III Promoter Humoral Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Pathway-restricted SMAD Protein Phosphorylation Nuclear Transport Catabolic Process Positive Regulation Of Humoral Immune Response
Tagcloud ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal	a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Difference) ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal	a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Intersection) ?