OAZ3 and ODC1

Number of citations of the paper that reports this interaction (PMID 18062773)
6

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		OAZ3	ODC1
Gene Name		ornithine decarboxylase antizyme 3	ornithine decarboxylase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Sperm Flagellum Blood Microparticle	Cellular_component Cytoplasm Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity Putrescine Transmembrane Transporter Activity Ankyrin Repeat Binding	Ornithine Decarboxylase Activity Protein Homodimerization Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Spermatogenesis Putrescine Transport Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Polyamine Transmembrane Transport	Kidney Development Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Positive Regulation Of Cell Proliferation Response To Virus Putrescine Biosynthetic Process From Ornithine Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Catabolic Process Small Molecule Metabolic Process
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate Spermine Putrescine Pyridoxine-5\'-Phosphate N-Pyridoxyl-Glycine-5-Monophosphate Alpha-Difluoromethylornithine N\'-Pyridoxyl-Lysine-5\'-Monophosphate G418
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AZIN1 AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 ODC1 REL SMAD1	9 interactors: AZI2 CSNK2B GORASP2 KAT5 OAZ1 OAZ2 OAZ3 SSR1 TK1
Entrez ID		51686	4953
HPRD ID		18670	01324
Ensembl ID		ENSG00000143450	ENSG00000115758
Uniprot IDs		Q6GMR0 Q9UMX2	P11926
PDB IDs			1D7K 2ON3 2OO0
Enriched GO Terms of Interacting Partners?		Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Cellular Biogenic Amine Metabolic Process Positive Regulation Of Polyamine Transmembrane Transport Amine Metabolic Process Ornithine Metabolic Process Regulation Of Protein Catabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Trans-Golgi Network Membrane Organization Putrescine Biosynthetic Process From Ornithine Regulation Of Cellular Amino Acid Metabolic Process Putrescine Transport Agmatine Biosynthetic Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Putrescine Biosynthetic Process Mesoderm Development Negative Regulation Of Polyamine Transmembrane Transport Gamete Generation Primary MiRNA Processing Positive Regulation Of Transport Osteoblast Fate Commitment Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Transcription From RNA Polymerase II Promoter SMAD Protein Complex Assembly Positive Regulation Of Interleukin-12 Biosynthetic Process Erythrocyte Maturation Alpha-amino Acid Metabolic Process Mesodermal Cell Fate Commitment Granulocyte Differentiation Kidney Development Regulation Of Interleukin-12 Biosynthetic Process Reproduction Renal System Development Positive Regulation Of Metabolic Process Macrophage Differentiation Cardiac Muscle Cell Proliferation Golgi To Plasma Membrane Protein Transport Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Urogenital System Development Regulation Of Cellular Process	Negative Regulation Of Polyamine Transmembrane Transport Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Protein Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Tumor Necrosis Factor Production Fetal Process Involved In Parturition Positive Regulation Of Metabolic Process Regulation Of Cellular Ketone Metabolic Process Skeletal Muscle Cell Proliferation Putrescine Transport Regulation Of Catalytic Activity Interferon-alpha Production Interleukin-6 Production Positive Regulation Of Intracellular Protein Transport Dendritic Cell Proliferation Response To Cortisol Thymidine Metabolic Process Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Biosynthetic Process Positive Regulation Of Intracellular Transport Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Positive Regulation Of Protein Modification Process Regulation Of Intracellular Protein Transport Endothelial Tube Morphogenesis Response To Hormone DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Type I Interferon Production Positive Regulation Of Protein Transport Positive Regulation Of Cellular Protein Metabolic Process Parturition Interferon-gamma Production Cellular Response To Estradiol Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration Small Molecule Metabolic Process Negative Regulation Of Interleukin-2 Production
Tagcloud ?		abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version	abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z
Tagcloud (Difference) ?		abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version	abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z
Tagcloud (Intersection) ?