OAZ1 and OAZ2

Number of citations of the paper that reports this interaction (PMID 15355308)
8

Data Source:
HPRD (two hybrid, in vitro)

		OAZ1	OAZ2
Gene Name		ornithine decarboxylase antizyme 1	ornithine decarboxylase antizyme 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Transport Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives	Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives
Drugs		L-Ornithine
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATXN1 EGFR OAZ2 OAZ3 ODC1 PIAS4 PSMB4 SMAD1	2 interactors: OAZ1 ODC1
Entrez ID		4946	4947
HPRD ID		03346	11966
Ensembl ID		ENSG00000104904	ENSG00000180304
Uniprot IDs		P54368	O95190
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyamine Biosynthetic Process Amine Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Regulation Of Nitrogen Compound Metabolic Process Cellular Biogenic Amine Metabolic Process Positive Regulation Of Metabolic Process Amine Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Biosynthetic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Alkanesulfonate Metabolic Process Putrescine Biosynthetic Process From Ornithine Positive Regulation Of Cellular Metabolic Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Keratinocyte Apoptotic Process Putrescine Transport Astrocyte Activation Regulation Of Response To DNA Damage Stimulus Regulation Of Apoptotic Process Putrescine Biosynthetic Process Regulation Of Cell Death Cellular Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Intracellular Protein Transport Tube Development Activation Of Phospholipase A2 Activity Positive Regulation Of Phospholipase A2 Activity Negative Regulation Of Catalytic Activity Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Reproductive Process Response To Cobalamin Response To UV-A Primary MiRNA Processing Multicellular Organism Reproduction Response To Hydroxyisoflavone Negative Regulation Of Mitotic Cell Cycle MAPK Cascade Gene Expression Ornithine Metabolic Process Osteoblast Fate Commitment	Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Putrescine Biosynthetic Process From Ornithine Putrescine Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Regulation Of Cellular Ketone Metabolic Process Ornithine Metabolic Process Negative Regulation Of Transmembrane Transport Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Intracellular Protein Transport
Tagcloud ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 srsf9 stimuli tardbp thoughts top tsp
Tagcloud (Difference) ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 srsf9 stimuli tardbp thoughts top tsp
Tagcloud (Intersection) ?