OAZ1 and OAZ2

Number of citations of the paper that reports this interaction (PubMedID 15355308)
42

Data Source:
HPRD (two hybrid, in vitro)

		OAZ1	OAZ2
Description		ornithine decarboxylase antizyme 1	ornithine decarboxylase antizyme 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Biogenic Amine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Biogenic Amine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs		Ornithine
Diseases
GWAS			Aluminium levels ( 26025379) Neuroticism ( 29255261)
Interacting Genes		13 interacting genes: AGTR1 ATXN1 EGFR HTR2B MYCBP2 NLGN3 NRIP1 OAZ2 OAZ3 ODC1 PIAS4 PSMB4 SMAD1	5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3
Entrez ID		4946	4947
HPRD ID		03346	11966
Ensembl ID		ENSG00000104904	ENSG00000180304
Uniprot IDs		J3QQY4 P54368	O95190
PDB IDs		4ZGY 4ZGZ 5BWA
Enriched GO Terms of Interacting Partners?		Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Polyamine Biosynthetic Process Biogenic Amine Metabolic Process Polyamine Metabolic Process Amine Metabolic Process Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Positive Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Viral Translational Frameshifting Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process System Process Transcription Coregulator Activity Cellular Response To Estradiol Stimulus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial Cell Proliferation Angiotensin Type I Receptor Activity Animal Organ Development Hair Follicle Development Regulation Of Protein Localization Nervous System Process Multivesicular Body, Internal Vesicle Lumen GTP Cyclohydrolase I Activity Ovarian Follicle Rupture Regulation Of Cellular Response To Stress MAPK Cascade Social Behavior Positive Regulation Of MiRNA Transcription Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of MiRNA Metabolic Process Bradykinin Receptor Binding Learning Or Memory Shc-EGFR Complex Endocytic Vesicle Homomeric SMAD Protein Complex Circadian Regulation Of Gene Expression Limb Epidermis Development Regulation Of Cell Population Proliferation Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Cytoplasm Cognition Regulation Of MiRNA Transcription Positive Regulation Of Protein Kinase C Signaling Ubiquitin Protein Ligase Binding	Polyamine Biosynthetic Process Polyamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Biogenic Amine Metabolic Process Amine Metabolic Process Bradykinin Receptor Activity Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine Signal Peptidase Complex Putrescine Biosynthetic Process Viral Translational Frameshifting Putrescine Metabolic Process Signal Peptide Processing Neurexin Family Protein Binding
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