SARAF and IFIT5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SARAF	IFIT5
Gene Name		store-operated calcium entry-associated regulatory factor	interferon-induced protein with tetratricopeptide repeats 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell
	Molecular Function	Protein Binding	TRNA Binding RNA Binding Single-stranded RNA Binding Poly(A) RNA Binding
	Biological Process	Calcium Ion Transport Regulation Of Store-operated Calcium Entry	Innate Immune Response Defense Response To Virus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ABCD4 IFIT5 RIBC2 SAT1 SNX15	15 interactors: A2M APOE CDC37 ECSIT IFIT1 IFIT3 LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2
Entrez ID		51669	24138
HPRD ID		08651	17130
Ensembl ID		ENSG00000133872	ENSG00000152778
Uniprot IDs		Q96BY9	B4DDV1 Q13325
PDB IDs			3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U
Enriched GO Terms of Interacting Partners?		Spermidine Acetylation Putrescine Catabolic Process Oxalate Transport Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Neurotransmitter Uptake 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Polyamine Biosynthetic Process Cobalamin Metabolic Process Amine Biosynthetic Process Polyamine Metabolic Process Sulfate Transmembrane Transport Sulfate Transport Neutral Amino Acid Transport	Positive Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Response To Stress Regulation Of Viral Process Negative Regulation Of Viral Genome Replication Cellular Response To Stimulus Negative Regulation Of Viral Process Immune Response Innate Immune Response Response To Stimulus Regulation Of Neuron Apoptotic Process Intracellular Signal Transduction Negative Regulation Of Protein Binding Regulation Of Neuron Death Oxidation-dependent Protein Catabolic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Nuclear Speck Organization Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Regulation Of MRNA Splicing, Via Spliceosome Defense Response Signal Transduction Immune System Process Positive Regulation Of Neuron Death Regulation Of Oxidoreductase Activity Regulation Of Cellular Process Regulation Of Apoptotic Process Protein Metabolic Process Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Regulation Of MRNA Processing Regulation Of Cell Death Signaling Regulation Of Catalytic Activity Negative Regulation Of Binding Negative Regulation Of Apoptotic Process Cell Communication Negative Regulation Of Programmed Cell Death Regulation Of RNA Splicing Response To Oxidative Stress Negative Regulation Of Helicase Activity Positive Regulation Of Phospholipid Efflux
Tagcloud ?			alternatively bias breadth bridged cap0 cap1 defense discrimination ends excluding expand ifits introduce intron methylguanosine monophosphate mutagenesis n7 processed repeats rnas specificities substitutions tetratricopeptide thermostable transcriptase triphosphate trnas
Tagcloud (Difference) ?			alternatively bias breadth bridged cap0 cap1 defense discrimination ends excluding expand ifits introduce intron methylguanosine monophosphate mutagenesis n7 processed repeats rnas specificities substitutions tetratricopeptide thermostable transcriptase triphosphate trnas
Tagcloud (Intersection) ?