IFIT5

Description		interferon induced protein with tetratricopeptide repeats 5
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GO Annotations	Cellular Component	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Membrane Ruffle Membrane Cell Projection Apical Part Of Cell
	Molecular Function	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	Immune System Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: A2M APOE CDC37 ECSIT H19 IFIT3 LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2 TTC3
Entrez ID		24138
HPRD ID		17130
Ensembl ID		ENSG00000152778
Uniprot IDs		Q13325
PDB IDs		3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Regulation Of Viral Genome Replication Regulation Of Viral Life Cycle Antioxidant Activity Amyloid Precursor Protein Metabolic Process Regulation Of Viral Process Regulation Of Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Response To Stress Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Magnesium Ion Binding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Respiratory Burst Involved In Inflammatory Response Oxidation-dependent Protein Catabolic Process Negative Regulation Of Complement Activation, Lectin Pathway Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle HSP90-CDC37 Chaperone Complex Regulation Of Blood Coagulation Regulation Of Hemostasis
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