IFIT5 and SARAF

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		IFIT5	SARAF
Description		interferon induced protein with tetratricopeptide repeats 5	store-operated calcium entry associated regulatory factor
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GO Annotations	Cellular Component	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Membrane Ruffle Membrane Cell Projection Apical Part Of Cell	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding	Protein Binding
	Biological Process	Immune System Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Store-operated Calcium Entry
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: A2M APOE CDC37 ECSIT H19 IFIT3 LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2 TTC3	7 interacting genes: ABCD4 HTR4 IFIT5 PDCD6 RIBC2 SAT1 SNX15
Entrez ID		24138	51669
HPRD ID		17130	08651
Ensembl ID		ENSG00000152778	ENSG00000133872
Uniprot IDs		Q13325	A0A140VK59 Q96BY9
PDB IDs		3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U	6O2U 6O2V 6O2W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Regulation Of Viral Genome Replication Regulation Of Viral Life Cycle Antioxidant Activity Amyloid Precursor Protein Metabolic Process Regulation Of Viral Process Regulation Of Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Response To Stress Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Magnesium Ion Binding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Respiratory Burst Involved In Inflammatory Response Oxidation-dependent Protein Catabolic Process Negative Regulation Of Complement Activation, Lectin Pathway Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle HSP90-CDC37 Chaperone Complex Regulation Of Blood Coagulation Regulation Of Hemostasis	Large Intestinal Transit ABC-type Vitamin B12 Transporter Activity Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding
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