SARAF and SNX15

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		SARAF	SNX15
Name		store-operated calcium entry associated regulatory factor	sorting nexin 15
Structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum-plasma Membrane Contact Site	Nucleolus Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Phosphatidylinositol Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Store-operated Calcium Entry	Intracellular Protein Transport Protein Transport
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: PRRG2
Interacting Genes		7 interacting genes: ABCD4 HTR4 IFIT5 PDCD6 RIBC2 SAT1 SNX15	6 interacting genes: ARL6IP1 KDM1A RABAC1 REEP6 RTN4 SARAF
Entrez ID		51669	29907
HPRD ID		08651	12073
Ensembl ID		ENSG00000133872	ENSG00000110025
Uniprot IDs		A0A140VK59 Q96BY9	Q9NRS6
PDB IDs		6O2U 6O2V 6O2W	6ECM 6MBI
GO Terms Enriched among Interactors		Large Intestinal Transit ABC-type Vitamin B12 Transporter Activity Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding	Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Membrane Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Epithelial To Mesenchymal Transition Telomeric Repeat-containing RNA Binding Mesenchymal Cell Differentiation FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Protein Localization To Endoplasmic Reticulum MRF Binding Protein Demethylase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Cell Migration Involved In Vasculogenesis Regulation Of Branching Morphogenesis Of A Nerve Intracellular Sphingolipid Homeostasis Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Response To Fungicide Guanine Metabolic Process Sec61 Translocon Complex Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Artery Morphogenesis Histone H3K4 Demethylase Activity Cerebral Cortex Radial Glia-guided Migration Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum-plasma Membrane Contact Site Regulation Of Artery Morphogenesis Histone H3K9 Demethylase Activity Positive Regulation Of Hepatocyte Proliferation Nuclear Pore Complex Assembly Regulation Of Toll-like Receptor 9 Signaling Pathway