CHMP2B and ATP5F1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP2B	ATP5F1C
Description		charged multivesicular body protein 2B	ATP synthase F1 subunit gamma
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GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Cytoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Postsynaptic Density Membrane Midbody Late Endosome Membrane Multivesicular Body Membrane Extracellular Exosome Glutamatergic Synapse Amphisome Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding Cadherin Binding	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Plasma Membrane Repair Autophagy Nucleus Organization Endosome Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Protein Transport Macroautophagy Viral Release From Host Cell Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Modulation Of Chemical Synaptic Transmission Cognition Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Neuron Cellular Homeostasis Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Modification Of Postsynaptic Structure Regulation Of Postsynapse Organization Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly	Oxidative Phosphorylation ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases		Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
GWAS		Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		14 interacting genes: ATP5F1C CENPF CFTR CHMP3 DPY30 FBXO7 MALSU1 PHGDH PNMA1 SNCA TERF2IP TRAF2 USP54 USP8	30 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FAM120A FBXO7 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337
Entrez ID		25978	509
HPRD ID		13174	00156
Ensembl ID		ENSG00000083937	ENSG00000165629
Uniprot IDs		A0A087WW88 B2RE76 Q9UQN3	B4DL14 P36542 Q8TAS0
PDB IDs		2JQK	8H9E 8H9F 8H9I 8H9J 8H9L 8H9M 8H9P 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Organelle Localization Midbody Dynein Complex Binding Regulation Of Exocytosis Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission TORC2 Complex Disassembly K63-linked Deubiquitinase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Phosphoglycerate Dehydrogenase Activity Negative Regulation Of Mitochondrial Translation	Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Cell Cycle Angiostatin Binding Regulation Of Peptidyl-serine Phosphorylation Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Process Positive Regulation Of Cell Migration Proton-transporting Two-sector ATPase Complex Neuron Projection Organization Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Postsynapse Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Neuron Projection Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Long-term Synaptic Potentiation Proton Motive Force-driven Mitochondrial ATP Synthesis Estrous Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Transcription-coupled Nucleotide-excision Repair Cognition Regulation Of Mitotic Cell Cycle Proton Motive Force-driven ATP Synthesis Transmembrane Transporter Complex Negative Regulation Of Cell Population Proliferation Proton-transporting ATP Synthase Activity, Rotational Mechanism Regulation Of Cell Cycle G1/S Phase Transition Regulation Of MiRNA Transcription ATP Biosynthetic Process Protein Tyrosine Kinase Activator Activity Negative Regulation Of Cell Cycle Regulation Of MiRNA Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Serine-type Endopeptidase Inhibitor Activity Regulation Of Epithelial Cell Proliferation MHC Class I Protein Binding Ovulation Cycle Dendritic Spine Morphogenesis Nervous System Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Auditory Stimulus Proton-transporting ATP Synthase Complex Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process
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