CHMP2B and CENPF

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		CHMP2B	CENPF
Gene Name		charged multivesicular body protein 2B	centromere protein F, 350/400kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Late Endosome Membrane Extracellular Vesicular Exosome	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Condensed Chromosome Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Nuclear Matrix Midbody Pronucleus Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Domain Specific Binding	Chromatin Binding Protein Binding Protein C-terminus Binding Transcription Factor Binding Protein Homodimerization Activity Dynein Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Membrane Organization Regulation Of Mitotic Spindle Assembly	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Mitotic Spindle Assembly Checkpoint Muscle Organ Development Cell Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Cell Differentiation Response To Drug Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly Regulation Of Cell Cycle DNA Biosynthetic Process
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion G2/M Transition Mitotic Anaphase Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Polo-like kinase mediated events Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Response to antineoplastic agents ( 21659360)
Protein-Protein Interactions		11 interactors: ATP5C1 CENPF CHMP3 DPY30 MALSU1 PHGDH PNMA1 TERF2IP TRAF2 USP54 USP8	10 interactors: BRAP CENPE CHMP2B FNTA FNTB NDEL1 NUP133 SNAP25 SVIL TOP3B
Entrez ID		25978	1063
HPRD ID		13174	02582
Ensembl ID		ENSG00000083937	ENSG00000117724
Uniprot IDs		B2RE76 Q9UQN3	P49454
PDB IDs		2JQK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Mitochondrial Translation Regulation Of Organelle Organization Negative Regulation Of Chromosome Organization Cell Division	Establishment Of Chromosome Localization Protein Farnesylation Chromosome Segregation Establishment Of Organelle Localization Nucleus Organization Protein Prenylation Organelle Localization Regulation Of Cell Cycle Regulation Of Rhodopsin Mediated Signaling Pathway Mitotic Metaphase Plate Congression Organelle Organization Rhodopsin Mediated Signaling Pathway Metaphase Plate Congression Nuclear Envelope Disassembly Mitotic Cell Cycle Process Regulation Of Cell Division Mitotic Cell Cycle Positive Regulation Of Cell Cycle Mitotic Nuclear Division Membrane Organization Nuclear Envelope Organization Cellular Protein Complex Assembly Positive Regulation Of Tubulin Deacetylation Phototransduction, Visible Light Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Cell Cycle Process Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Establishment Of Localization In Cell Detection Of Light Stimulus Regulation Of Cell Cycle Process Regulation Of Mitotic Nuclear Division Mitotic Chromosome Movement Towards Spindle Pole Cellular Response To Radiation Cell Cycle Wound Healing Cellular Localization Cellular Macromolecular Complex Assembly Regulation Of Tubulin Deacetylation Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Axon Regeneration Positive Regulation Of Deacetylase Activity Response To Wounding Retrograde Axon Cargo Transport Viral Budding Via Host ESCRT Complex Viral Life Cycle
Tagcloud ?		c9orf72 complexities counseling ethical fad familial frame frontotemporal ftd fus genetics grn gwas helping hexanucleotide mapt modifying multifactorial navigate pathogenetic presenilin progranulin psen1 psen2 reading tarbdp tardna valosin vcp	assembled causal computational coordinated cross drivers engineered foxm1 genetically genome indicator interactomes interrogation malignancy master networks profiles promote prostate regulators regulatory represents robust shows synergistic synergistically validation valuable wide
Tagcloud (Difference) ?		c9orf72 complexities counseling ethical fad familial frame frontotemporal ftd fus genetics grn gwas helping hexanucleotide mapt modifying multifactorial navigate pathogenetic presenilin progranulin psen1 psen2 reading tarbdp tardna valosin vcp	assembled causal computational coordinated cross drivers engineered foxm1 genetically genome indicator interactomes interrogation malignancy master networks profiles promote prostate regulators regulatory represents robust shows synergistic synergistically validation valuable wide
Tagcloud (Intersection) ?