PTRH2 and TUBD1

Data Source: HiPPIP (Novel)

		PTRH2	TUBD1
Name		peptidyl-tRNA hydrolase 2	tubulin delta 1
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Centriole Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Cell Projection
	Molecular Function	Peptidyl-tRNA Hydrolase Activity Protein Binding Hydrolase Activity	Nucleotide Binding Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Apoptotic Process Negative Regulation Of Gene Expression Positive Regulation Of Anoikis Negative Regulation Of Anoikis	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway
Pathways		Ub-specific processing proteases	None
Drugs		None	Vinblastine
GWAS		No GWAS studies recorded	C-reactive protein levels ( 30388399 ) Chronotype ( 30696823 ) Crohn's disease ( 28067908 ) Eosinophil count ( 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Hemoglobin levels ( 32327693 ) Inflammatory bowel disease ( 23128233 ) Mean reticulocyte volume ( 32888494 ) Monocyte count ( 29403010 ) Obesity-related traits ( 23251661 ) Red blood cell count ( 32888494 ) Red cell distribution width ( 27863252 28957414 32888494 ) Systolic blood pressure ( 30578418 )
Novel Interactors		1 novel interactors: TUBD1	6 novel interactors: EPX GJB3 PTRH2 RFX5 TMED1 TRPV1
Interacting Genes		1 interacting genes: TLE5	1 interacting genes: TOP1
Entrez ID		51651	51174
HPRD ID		12273	06297
Ensembl ID		ENSG00000141378	ENSG00000108423
Uniprot IDs		J3KQ48 Q9Y3E5	Q9UJT1
PDB IDs		1Q7S	Not available
GO Terms Enriched among Interactors		None	Response To Purine-containing Compound DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Cellular Response To Luteinizing Hormone Stimulus Dense Fibrillar Component Response To Temperature Stimulus Detection Of Temperature Stimulus Involved In Thermoception Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Temperature-gated Ion Channel Activity Smooth Muscle Contraction Involved In Micturition Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Thermoception Response To Capsazepine Lactoperoxidase Activity Defense Response To Nematode Peptidyl-tRNA Hydrolase Activity