LYST and CELF4

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
BioGRID (two hybrid)

		LYST	CELF4
Gene Name		lysosomal trafficking regulator	CUGBP, Elav-like family member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding	Nucleotide Binding Translation Repressor Activity, Nucleic Acid Binding MRNA Binding BRE Binding
	Biological Process	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Germ Cell Development Embryo Development Negative Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	2 interactors: APP LYST
Entrez ID		1130	56853
HPRD ID		06060	12534
Ensembl ID		ENSG00000143669	ENSG00000101489
Uniprot IDs		Q99698	M0QY66 Q9BZC1 S4R3V5
PDB IDs			2DGP 2DNK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing	Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Synaptic Growth At Neuromuscular Junction Mast Cell Secretory Granule Organization Collateral Sprouting In Absence Of Injury Blood Coagulation Hemostasis Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Endosome Transport Via Multivesicular Body Sorting Pathway Secretion By Cell Axon Choice Point Recognition Ion Homeostasis Secretion Of Lysosomal Enzymes Regulation Of Body Fluid Levels Wound Healing Chemotaxis Secretion Neuron Remodeling Phospholipid Homeostasis Response To Wounding Microtubule-based Process Innate Immune Response Chemical Homeostasis Cellular Copper Ion Homeostasis Early Endosome To Late Endosome Transport Neutrophil Mediated Immunity Melanosome Organization Pigment Granule Organization Copper Ion Homeostasis Suckling Behavior Defense Response To Protozoan Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Activation Natural Killer Cell Mediated Immunity Response To Protozoan Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Mating Behavior Locomotion Endoplasmic Reticulum Calcium Ion Homeostasis Lipid Metabolic Process Immune Response RNA Polyadenylation Neuron Recognition Defense Response
Tagcloud ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?