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LYST and HNRNPM
Number of citations of the paper that reports this interaction (PubMedID
11984006
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid, in vivo)
LYST
HNRNPM
Description
lysosomal trafficking regulator
heterogeneous nuclear ribonucleoprotein M
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Microtubule Cytoskeleton
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Membrane
Nuclear Matrix
Paraspeckles
Synapse
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Protein Domain Specific Binding
Biological Process
Lymphocyte Mediated Immunity
Phagocytosis
Immune Response
Protein Transport
Leukocyte Chemotaxis
Melanosome Organization
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Mast Cell Secretory Granule Organization
Natural Killer Cell Mediated Cytotoxicity
Defense Response To Bacterium
Defense Response To Protozoan
Pigmentation
Defense Response To Virus
Defense Response To Other Organism
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Basophil percentage of white cells (
32888494
)
Lymphocyte count (
32888494
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Systemic lupus erythematosus (
19838195
26502338
)
Appendicular lean mass (
33097823
)
Coronary artery disease (
29212778
)
Interacting Genes
23 interacting genes:
ATN1
CALM1
CELF4
CNTROB
CPAP
CSNK2B
DNAJC14
EFS
ESRRA
ESS2
HGS
HNRNPM
KPNB1
MED12
MRPL17
MRPS31
NCDN
PCBP4
TNNI3
VTA1
YWHAB
YWHAQ
ZNF521
117 interacting genes:
AKAP9
APC
CDC5L
CEACAM5
DUX4
ECPAS
FXR1
FXR2
GMCL2
GSK3A
GSK3B
HGS
HNRNPF
HNRNPH1
JUN
LENG8
LINC00624
LMO1
LMO2
LMO3
LONRF2
LYST
MAGEA6
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
OGT
PLRG1
PRRC2A
RBM4
RBM4B
SMARCB1
STAT3
SUMO2
TCERG1
TEKT4
TNKS
TRAF1
TSC1
TSGA10
U2AF1
UBC
UBE2I
USP7
WDR77
WEE2-AS1
YWHAG
ZNF207
Entrez ID
1130
4670
HPRD ID
06060
01188
Ensembl ID
ENSG00000143669
ENSG00000099783
Uniprot IDs
Q99698
P52272
Q59ES8
PDB IDs
2DGV
2DH9
2DO0
2OT8
Enriched GO Terms of Interacting Partners
?
Protein Domain Specific Binding
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Calcium Channel Inhibitor Activity
Astral Microtubule Organization
Ribonucleoprotein Complex
Alternative MRNA Splicing, Via Spliceosome
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Centriole Replication
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Multivesicular Body Organization
Multivesicular Body Assembly
Centriole Assembly
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
Positive Regulation Of MRNA Catabolic Process
RNA Destabilization
Positive Regulation Of MRNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Translation
Negative Regulation Of Cell Migration
Regulation Of Metabolic Process
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Negative Regulation Of Angiogenesis
Negative Regulation Of Cytokine Production
Negative Regulation Of Vasculature Development
Regulation Of Angiogenesis
Regulation Of MRNA Stability
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Vasculature Development
Regulation Of RNA Stability
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Developmental Process
Regulation Of MRNA Metabolic Process
Negative Regulation Of Signal Transduction
Regulation Of Cell Migration
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Cell Motility
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cellular Response To Growth Factor Stimulus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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