Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ANAPC11 and CAPN11
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
ANAPC11
CAPN11
Gene Name
anaphase promoting complex subunit 11
calpain 11
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Anaphase-promoting Complex
Nucleolus
Cytosol
Acrosomal Vesicle
Cytoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Protein Ligase Activity
Cullin Family Protein Binding
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Peptidase Activity
Biological Process
Mitotic Cell Cycle
Mitotic Nuclear Division
Mitotic Spindle Assembly Checkpoint
Protein Ubiquitination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Division
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein K11-linked Ubiquitination
Proteolysis
Pathways
Phosphorylation of the APC/C
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Antigen processing: Ubiquitination & Proteasome degradation
Separation of Sister Chromatids
Inactivation of APC/C via direct inhibition of the APC/C complex
Cellular Senescence
Mitotic Anaphase
APC/C:Cdc20 mediated degradation of Securin
M Phase
Inactivation of APC/C via direct inhibition of the APC/C complex
Autodegradation of Cdh1 by Cdh1:APC/C
Mitotic Spindle Checkpoint
Class I MHC mediated antigen processing & presentation
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Cell Cycle, Mitotic
APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cell Cycle Checkpoints
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Mitotic Metaphase and Anaphase
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
27 interactors:
ANAPC1
ANAPC10
ANAPC2
CAPN11
CCNB1
CDC16
CDC25A
CDC34
CDH1
CUL5
FBXO5
HECW2
KIF18A
MAK
MLKL
NKD2
PTTG1
RNF111
TRIM65
UBC
UBE2C
UBE2D1
UBE2D2
UBE2K
UBE2S
UBE2U
ZAP70
4 interactors:
ANAPC11
PRKAR1A
UNG
XRCC6
Entrez ID
51529
11131
HPRD ID
12452
05315
Ensembl ID
ENSG00000141552
ENSG00000137225
Uniprot IDs
Q9NYG5
Q9UMQ6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Polyubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination
Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Proteolysis
Mitotic Cell Cycle Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Mitotic Cell Cycle
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Transferase Activity
Protein K11-linked Ubiquitination
Catabolic Process
Mitotic Nuclear Division
Positive Regulation Of Protein Catabolic Process
Cell Cycle Process
Negative Regulation Of Protein Ubiquitination
Regulation Of Protein Catabolic Process
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Regulation Of Chromosome Segregation
Cell Cycle
Regulation Of Proteolysis
Regulation Of Mitotic Sister Chromatid Separation
Protein Metabolic Process
Cell Division
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Mitotic Spindle Assembly Checkpoint
Negative Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cell Division
Cellular Hyperosmotic Salinity Response
DNA Recombination
Regulation Of Cell Division
Depyrimidination
Negative Regulation Of Transferase Activity
Cellular Response To X-ray
Base-excision Repair, AP Site Formation
Pyrimidine Deoxyribonucleotide Catabolic Process
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Establishment Of Integrated Proviral Latency
Cellular Hyperosmotic Response
Hyperosmotic Salinity Response
Establishment Of Viral Latency
Cellular Response To Salt Stress
Negative Regulation Of Cell Cycle
Regulation Of CAMP-dependent Protein Kinase Activity
DNA Ligation
Regulation Of Cell Cycle Process
Activation Of Protein Kinase A Activity
Negative Regulation Of Meiotic Nuclear Division
Negative Regulation Of Cellular Metabolic Process
Somatic Hypermutation Of Immunoglobulin Genes
Somatic Diversification Of Immune Receptors Via Somatic Mutation
Immune System Process
Cardiac Muscle Cell Proliferation
Deoxyribose Phosphate Catabolic Process
Viral Process
Positive Regulation Of Transferase Activity
Double-strand Break Repair Via Nonhomologous End Joining
Negative Regulation Of Meiotic Cell Cycle
DNA Repair
Protein K11-linked Ubiquitination
Hyperosmotic Response
Cardiac Muscle Tissue Growth
Deoxyribonucleotide Catabolic Process
Positive Regulation Of Cellular Metabolic Process
V(D)J Recombination
Renal Water Homeostasis
Cellular Response To Osmotic Stress
Immune System Development
Response To X-ray
Female Meiotic Division
Mitotic Spindle Assembly Checkpoint
Somatic Recombination Of Immunoglobulin Gene Segments
Regulation Of Meiosis
Spindle Assembly Checkpoint
Negative Regulation Of Catalytic Activity
Response To Salt Stress
Somatic Diversification Of Immunoglobulins
Tagcloud
?
afg3l2
arf1
calgizzarin
cki
dci
dph2l
fb1
fxyd6
gif
gp96
gpr85
hhp2
kpdxm
ksp
mrps7
ohs
osteosarcomas
ought
p110
phosphoglucoisomerase
rpl13a
rpl35a
s11
sec34
skd3
subtracted
subtractive
sulphonase
tapa
Tagcloud (Difference)
?
afg3l2
arf1
calgizzarin
cki
dci
dph2l
fb1
fxyd6
gif
gp96
gpr85
hhp2
kpdxm
ksp
mrps7
ohs
osteosarcomas
ought
p110
phosphoglucoisomerase
rpl13a
rpl35a
s11
sec34
skd3
subtracted
subtractive
sulphonase
tapa
Tagcloud (Intersection)
?