ANAPC11 and BANP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ANAPC11	BANP
Description		anaphase promoting complex subunit 11	BTG3 associated nuclear protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Anaphase-promoting Complex Nucleolus Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body Nuclear Speck
	Molecular Function	G Protein-coupled Receptor Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Cullin Family Protein Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Regulation Of Meiotic Cell Cycle Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein Branched Polyubiquitination	Chromatin Organization
Pathways		Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase APC/C:Cdc20 mediated degradation of mitotic proteins Phosphorylation of the APC/C APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Senescence-Associated Secretory Phenotype (SASP) Assembly of the pre-replicative complex CDK-mediated phosphorylation and removal of Cdc6 Transcriptional Regulation by VENTX Aberrant regulation of mitotic exit in cancer due to RB1 defects Antigen processing: Ubiquitination & Proteasome degradation	Regulation of TP53 Activity through Association with Co-factors Degradation of CDH1
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 20719862 28171582) Corneal structure ( 23291589) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Keratoconus ( 33649486) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		58 interacting genes: ANAPC10 ANAPC2 BANP BEND2 CAPN11 CCNB1 CDC16 CDC20 CREB5 CRYBA2 CUL5 CYSRT1 DTX2 EFEMP1 EFEMP2 FBXO5 FOXO3 FRS3 FZR1 GPANK1 H2AC4 H2BC3 H3C1 HSD3B7 IQUB KRTAP11-1 KRTAP13-2 KRTAP19-2 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 MAK MGAT5B MLKL NKD2 OXER1 P4HA3 PRKAA2 PRKAB2 PTTG1 RBPMS RNF111 SPMIP9 TCEANC TLE5 TRIM65 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2L1 UBE2S UBE2U WWOX ZAP70	193 interacting genes: ABLIM3 ADAM15 AFG1L ALAS2 ANAPC11 ANKRD55 ANTKMT ARID5A ATF2 ATXN7L2 BAG5 BICRAL BLZF1 BOC BTG3 C1orf94 C1QTNF2 C22orf15 C22orf39 C3orf36 CAMK2D CBX8 CCDC26 CCDC74B CDC7 CDSN CDX4 CEP76 CFAP206 CHRDL2 COL10A1 CRX CSNK2B CTSZ CYTOR DCDC2B DLX3 DNAJA4 ENKD1 EPHA10 ESM1 FAM117B FAM120C FAM217B FAM222B FAM90A1 FARS2 FHL2 FHL5 FLOT1 FOXM1 FOXR1 GARIN6 GAS2L2 GFM2 GOLGA6L9 HAPLN2 HEYL HHIPL1 HIVEP1 HMGB3P1 HNRNPLL HSFY1 IDO2 IGF1 IGFN1 INO80B ISCU KCTD9 KHDC4 KLF15 KRTAP8-1 L3MBTL3 LAP3 LENG1 LGALS14 LGALS4 LHX4 LHX8 LIN54 LINC01547 LMO1 LMO2 LMO3 LMO4 LRIF1 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MSRB3 MTERF4 MVP NEDD9 NFYA NMNAT1 NOTO NRIP2 PANX2 PARD6B PAX6 PHF21A PHF21B PID1 PIH1D2 PIK3C2G PIM1 PML PNRC2 POGZ POLDIP3 POLR2L POU6F2 PPIB PPIC PPIF PRDM6 PRKAB2 PRKCH PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRR34 PSMD9 PSORS1C2 RAB3IP RAD54L2 RBM39 RBPMS REL RELA RHNO1 RHOH RHOQ RIDA RIMS3 RPP25 RYBP SAPCD1 SCN5A SH3RF2 SLC16A3 SLC19A4P SNAPIN SNRPB SNX5 SP2 SP4 SPACA6 SPANXN2 SPMIP2 SRARP STK38 STOX1 TAF6 TERF2 TERF2IP TNXB TOX TOX4 TP53 TRAF2 TRAF4 TRIM35 TROAP TTC23 UBAP2 UBE2I VEZF1 XAGE1B YJU2 ZBTB4 ZC2HC1C ZMIZ2 ZMYM6 ZNF410 ZNF438 ZNF471 ZNF474 ZNF488 ZNF512B ZNF580 ZNF581
Entrez ID		51529	54971
HPRD ID		12452	16538
Ensembl ID		ENSG00000141552	ENSG00000172530
Uniprot IDs		Q9NYG5	A0A0S2Z5C2 A0A0S2Z5M2 A0A804HKG3 B3KM38 B4DE54 Q8N9N5
PDB IDs		2MT5 4R2Y 4UI9 5A31 5G04 5G05 5JG6 5KHR 5KHU 5L9T 5L9U 5LCW 6Q6G 6Q6H 6TLJ 6TM5 6TNT 8PKP 8TAR 8TAU 9GAW	7YUG 7YUK 8HTX 8YZT
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Protein Modification By Small Protein Conjugation Anaphase-promoting Complex Protein K11-linked Ubiquitination Protein K48-linked Ubiquitination Post-translational Protein Modification Ubiquitin Conjugating Enzyme Activity Modification-dependent Protein Catabolic Process Protein Modification Process Positive Regulation Of Ubiquitin Protein Ligase Activity Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Anaphase-promoting Complex Binding Regulation Of Ubiquitin-protein Transferase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Meiotic Cell Cycle Proteasomal Protein Catabolic Process Intermediate Filament Macromolecule Catabolic Process Proteolysis Free Ubiquitin Chain Polymerization Regulation Of Sister Chromatid Segregation Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Sister Chromatid Separation Ubiquitin-protein Transferase Activity Cell Division Regulation Of Protein Ubiquitination Positive Regulation Of Post-translational Protein Modification Regulation Of Chromosome Segregation Regulation Of Chromosome Separation Protein Catabolic Process Regulation Of Nuclear Division Protein Metabolic Process Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Cytosol Cell Cycle Phase Transition Regulation Of Post-translational Protein Modification Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitotic Metaphase/anaphase Transition Protein Branched Polyubiquitination Ubiquitin-like Protein Transferase Activity Regulation Of Reproductive Process Positive Regulation Of Cell Cycle Phase Transition SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Nuclear Division Positive Regulation Of Mitotic Sister Chromatid Separation	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Protein Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Chromatin Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA Binding Positive Regulation Of Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleoplasm RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Zinc Ion Binding Sequence-specific Double-stranded DNA Binding Cyclosporin A Binding Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of RNA Metabolic Process Protein Kinase Binding Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Cyclin-dependent Protein Kinase Activity
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