CAPN11

Description		calpain 11
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytoplasmic Vesicle
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Proteolysis
Pathways		Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ANAPC11 PRKAR1A UNG XRCC6
Entrez ID		11131
HPRD ID		05315
Ensembl ID		ENSG00000137225
Uniprot IDs		Q9UMQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Damaged DNA Binding Cellular Response To X-ray Double-strand Break Repair Via Classical Nonhomologous End Joining Hyperosmotic Salinity Response DNA End Binding Cellular Hyperosmotic Salinity Response Nuclear Telomere Cap Complex DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Cellular Response To Salt Stress DNA-dependent Protein Kinase Complex Ku70:Ku80 Complex Double-stranded Telomeric DNA Binding Nonhomologous End Joining Complex DNA Recombination CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Nucleotide-activated Protein Kinase Complex Cellular Response To Glucagon Stimulus Base-excision Repair, AP Site Formation Via Deaminated Base Removal Single Strand Break Repair Uracil DNA N-glycosylase Activity Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Depyrimidination Cellular Hyperosmotic Response Telomeric DNA Binding Hyperosmotic Response Response To X-ray DNA Repair Regulation Of Lymphocyte Activation Cellular Response To Gamma Radiation Response To Salt Stress Cardiac Muscle Cell Proliferation CAMP Binding Protein Kinase A Catalytic Subunit Binding Response To Glucagon Negative Regulation Of Activated T Cell Proliferation Sperm Head-tail Coupling Apparatus Negative Regulation Of CAMP/PKA Signal Transduction Somatic Hypermutation Of Immunoglobulin Genes Deoxyribose Phosphate Catabolic Process Isotype Switching Base-excision Repair, AP Site Formation Ribosomal Small Subunit Binding Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Diversification Of Immune Receptors Via Somatic Mutation Deoxyribonucleotide Catabolic Process Pyrimidine Deoxyribonucleotide Catabolic Process DNA Modification
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