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ANAPC7 and UBE2S
Number of citations of the paper that reports this interaction (PMID
25306923
)
0
Data Source:
BioGRID
(pull down)
ANAPC7
UBE2S
Gene Name
anaphase promoting complex subunit 7
ubiquitin-conjugating enzyme E2S
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Anaphase-promoting Complex
Cytoplasm
Molecular Function
Protein Phosphatase Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Mitotic Cell Cycle
Mitotic Nuclear Division
Mitotic Spindle Assembly Checkpoint
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Division
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein K11-linked Ubiquitination
Cellular Protein Modification Process
Exit From Mitosis
Free Ubiquitin Chain Polymerization
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Cell Division
Activation Of Anaphase-promoting Complex Activity
Protein K63-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Phosphorylation of the APC/C
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Antigen processing: Ubiquitination & Proteasome degradation
Separation of Sister Chromatids
Inactivation of APC/C via direct inhibition of the APC/C complex
Cellular Senescence
Mitotic Anaphase
APC/C:Cdc20 mediated degradation of Securin
M Phase
Inactivation of APC/C via direct inhibition of the APC/C complex
Autodegradation of Cdh1 by Cdh1:APC/C
Mitotic Spindle Checkpoint
Class I MHC mediated antigen processing & presentation
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Cell Cycle, Mitotic
APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cell Cycle Checkpoints
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Mitotic Metaphase and Anaphase
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
ANAPC10
ANAPC2
ANAPC4
BUB1B
CDC16
CDC20
CDC27
CDH1
CDT1
CREBBP
FBXO5
FZR1
UBC
UBE2S
29 interactors:
ANAPC1
ANAPC11
ANAPC2
ANAPC4
ANAPC5
ANAPC7
APP
ATXN3
BIRC2
CDC16
CDC20
CDC23
CDC27
CYLD
FZR1
OTUB1
OTUD7B
RBCK1
STAMBP
UBA1
UBA6
UBC
UCHL3
USP15
USP2
USP21
USP5
USP7
ZRANB1
Entrez ID
51434
27338
HPRD ID
16233
15603
Ensembl ID
ENSG00000196510
ENSG00000108106
Uniprot IDs
Q4KMX6
Q69YV3
Q9UJX3
Q16763
PDB IDs
3FFL
1ZDN
Enriched GO Terms of Interacting Partners
?
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Cell Cycle Checkpoint
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Mitotic Cell Cycle Process
Negative Regulation Of Transferase Activity
Regulation Of Mitotic Sister Chromatid Separation
Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Catabolic Process
Protein Catabolic Process
Regulation Of Cell Division
Cell Division
Negative Regulation Of Cellular Protein Catabolic Process
Mitotic Spindle Assembly Checkpoint
Cell Cycle Process
Spindle Assembly Checkpoint
Negative Regulation Of Cell Division
Regulation Of Chromosome Segregation
Mitotic Spindle Checkpoint
Positive Regulation Of Proteolysis
Protein Polyubiquitination
Negative Regulation Of Chromosome Segregation
Negative Regulation Of Mitotic Nuclear Division
Spindle Checkpoint
Regulation Of Mitotic Metaphase/anaphase Transition
Cellular Macromolecule Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Proteolysis
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Protein K11-linked Ubiquitination
Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Ubiquitination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Protein Modification Process
Positive Regulation Of Ligase Activity
Regulation Of Proteolysis
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Mitotic Spindle Assembly Checkpoint
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Spindle Assembly Checkpoint
Regulation Of Protein Ubiquitination
Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Mitotic Spindle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Chromosome Segregation
Protein Polyubiquitination
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Spindle Checkpoint
Negative Regulation Of Chromosome Organization
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Catabolic Process
Protein Deubiquitination
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Protein Metabolic Process
Protein Modification By Small Protein Removal
Protein Ubiquitination
Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud
?
arising
cluster
clusters
coexpressed
coexpression
conjugating
coregulated
endpoints
example
examples
friendly
glados
guilt
http
ie
kcnk5
messenger
modules
online
outputs
potassium
powerful
subfamily
ucd
uncovered
user
weighted
wgcna
Tagcloud (Difference)
?
arising
cluster
clusters
coexpressed
coexpression
conjugating
coregulated
endpoints
example
examples
friendly
glados
guilt
http
ie
kcnk5
messenger
modules
online
outputs
potassium
powerful
subfamily
ucd
uncovered
user
weighted
wgcna
Tagcloud (Intersection)
?