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CSAD and NR1H2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CSAD
NR1H2
Gene Name
cysteine sulfinic acid decarboxylase
nuclear receptor subfamily 1, group H, member 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Sulfinoalanine Decarboxylase Activity
Pyridoxal Phosphate Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Sequence-specific Transcription Regulatory Region DNA Binding RNA Polymerase II Transcription Factor Recruiting Transcription Factor Activity
DNA Binding
Steroid Hormone Receptor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Apolipoprotein A-I Receptor Binding
Retinoid X Receptor Binding
ATPase Binding
Biological Process
Sulfur Amino Acid Metabolic Process
Sulfur Amino Acid Catabolic Process
Cellular Nitrogen Compound Metabolic Process
Taurine Biosynthetic Process
Small Molecule Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cholesterol Efflux
Positive Regulation Of Lipid Storage
Negative Regulation Of Cholesterol Storage
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Lipid Transport
Positive Regulation Of Cholesterol Transport
Cholesterol Homeostasis
Steroid Hormone Mediated Signaling Pathway
Cellular Lipid Metabolic Process
Positive Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Proteolysis
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Retinoic Acid Receptor Signaling Pathway
Negative Regulation Of Pinocytosis
Positive Regulation Of Lipoprotein Lipase Activity
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of High-density Lipoprotein Particle Assembly
Positive Regulation Of Pancreatic Juice Secretion
Positive Regulation Of Secretion Of Lysosomal Enzymes
Regulation Of Cholesterol Homeostasis
Pathways
Degradation of cysteine and homocysteine
Sulfur amino acid metabolism
Metabolism of amino acids and derivatives
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Pyridoxal Phosphate
L-Cysteine
(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid
Benzenesulfonyl
N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
10 interactors:
ANXA1
ANXA7
CDKN1A
GSK3B
NR1H2
PIN1
RAP1B
RCC1
SMN1
TK1
46 interactors:
BAG6
C14orf1
CDKN1A
CHD3
COL4A5
CSAD
DUSP12
FAF1
FOXO3
HDAC4
HMGXB4
ING3
KDM1A
LAMC3
MDFI
MED1
MPP1
NCOA3
NCOA6
NCOR1
NCOR2
NPY
NR0B2
NRIP1
PCDH17
PRKCA
RARA
RMI1
ROBO2
RXRA
RXRB
RXRG
SCG5
SIRT1
SMPD1
SORBS2
SPRY2
SRC
SUV39H1
TMEM161A
UBE2D1
UBE2I
VDR
VIM
YY1
ZXDC
Entrez ID
51380
7376
HPRD ID
16763
02660
Ensembl ID
ENSG00000139631
ENSG00000131408
Uniprot IDs
Q86V02
Q96JQ3
Q9Y600
B4DNM6
F1D8P7
M0R2F9
P55055
PDB IDs
2JIS
1P8D
1PQ6
1PQ9
1PQC
1UPV
1UPW
3KFC
3L0E
4DK7
4DK8
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Component Organization
Response To Organic Cyclic Compound
Response To Organic Substance
Regulation Of Catalytic Activity
Positive Regulation Of Catalytic Activity
Negative Regulation Of Transport
Positive Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Ras GTPase Activity
Response To Inorganic Substance
Response To Steroid Hormone
Regulation Of Cellular Localization
Positive Regulation Of Hydrolase Activity
Response To Glucocorticoid
Regulation Of Cell Cycle Process
Cellular Response To Organic Substance
Response To Corticosteroid
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Ras GTPase Activity
Epithelial Cell Differentiation
Response To X-ray
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Protein Transport
Neurotrophin Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Ras Protein Signal Transduction
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of GTPase Activity
Regulation Of Protein Localization
Positive Regulation Of Cellular Metabolic Process
Response To Lipid
Positive Regulation Of Lipid Biosynthetic Process
Positive Regulation Of Phosphorylation
Response To Metal Ion
Cellular Response To Heat
Positive Regulation Of Protein Modification Process
Tissue Development
Regulation Of Organelle Organization
Regulation Of Vesicle-mediated Transport
Regulation Of Cell Cycle
Response To Hormone
Positive Regulation Of High-density Lipoprotein Particle Assembly
Neutrophil Clearance
Positive Regulation Of Secretion Of Lysosomal Enzymes
Positive Regulation Of Pancreatic Juice Secretion
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Organ Development
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Response To Organic Substance
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Reproductive Structure Development
Reproductive System Development
System Development
Positive Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Response To Hormone
Multicellular Organismal Development
Cell Differentiation
Single Organism Reproductive Process
Anatomical Structure Development
Developmental Process Involved In Reproduction
Developmental Process
Reproductive Process
Cellular Response To Steroid Hormone Stimulus
Signal Transduction
Multicellular Organismal Reproductive Process
Multicellular Organism Reproduction
Cellular Response To Organic Substance
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of RNA Biosynthetic Process
Chromatin Organization
Response To Stimulus
Hormone-mediated Signaling Pathway
Regulation Of RNA Metabolic Process
Gene Expression
Positive Regulation Of Transcription, DNA-templated
Signaling
Tagcloud
?
ado
birth
blotting
born
cdo
deficiency
died
disruption
drinking
engineered
g2
g3
gpx
hplc
indicated
ko
lactoferrin
northern
offspring
physiological
prolactin
restored
southern
studying
supplementation
survived
taurine
taut
verified
Tagcloud (Difference)
?
ado
birth
blotting
born
cdo
deficiency
died
disruption
drinking
engineered
g2
g3
gpx
hplc
indicated
ko
lactoferrin
northern
offspring
physiological
prolactin
restored
southern
studying
supplementation
survived
taurine
taut
verified
Tagcloud (Intersection)
?