POP5 and RPP14

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro)

		POP5	RPP14
Description		POP5 ribonuclease P/MRP subunit	ribonuclease P/MRP subunit p14
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex	Nucleus Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex Endoribonuclease Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing	TRNA 5'-leader Removal TRNA Processing
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Chronotype ( 30696823) High light scatter reticulocyte count ( 27863252) Intake of total sugars ( 31005972)	Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)
Interacting Genes		16 interacting genes: CAMK2B CCDC102B CEP44 DCDC2 INCA1 KRT34 KRT40 NDUFAB1 POP1 POP4 REL RPP14 RPP25 TRAF1 UBC USHBP1	22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277
Entrez ID		51367	11102
HPRD ID		15158	18001
Ensembl ID		ENSG00000167272	ENSG00000163684
Uniprot IDs		Q969H6	O95059
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Ribonuclease MRP Complex Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Centriole-centriole Cohesion Structural Molecule Activity Acyl Carrier Activity Structural Constituent Of Skin Epidermis Cytoskeleton	Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Metabolic Process RRNA Processing Ribonuclease P Complex TRNA Processing RRNA Metabolic Process RNA Processing Nucleolus Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Nucleic Acid Metabolic Process Nucleus Actin Filament Uncapping Ribonuclease MRP Activity
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