PLAC8 and TRIP13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLAC8	TRIP13
Gene Name		placenta-specific 8	thyroid hormone receptor interactor 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Male Germ Cell Nucleus Nucleus
	Molecular Function	Chromatin Binding	Transcription Cofactor Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Cell Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Brown Fat Cell Differentiation	Oocyte Maturation Double-strand Break Repair Transcription From RNA Polymerase II Promoter Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: COPS5 RBPMS TRIP13	75 interactors: ADAM15 AMDHD2 ARL11 ARSA ASB13 C11orf54 C4orf33 CARD14 CCBL1 CD99 COMT CPSF3L CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1BP MAD2L2 METTL15 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 PARK2 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA QARS RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TLDC1 TNRC6A TPT1 WDYHV1 ZNF34 ZNF655
Entrez ID		51316	9319
HPRD ID		06335	05145
Ensembl ID		ENSG00000145287	ENSG00000071539
Uniprot IDs		Q9NZF1	Q15645
PDB IDs
Enriched GO Terms of Interacting Partners?		Exosomal Secretion Transcription, DNA-templated Cullin Deneddylation RNA Biosynthetic Process Protein Deneddylation Female Meiosis I Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus RNA Metabolic Process Synaptonemal Complex Assembly Oocyte Maturation Synaptonemal Complex Organization Gene Expression Cellular Macromolecule Biosynthetic Process Male Meiosis I Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Female Meiotic Division Reciprocal Meiotic Recombination Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Oocyte Development Oocyte Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Synapsis Homologous Chromosome Segregation Nucleobase-containing Compound Metabolic Process Male Meiosis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Oogenesis Meiotic Chromosome Segregation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Import Into Nucleus Nitrogen Compound Metabolic Process Meiosis I Protein Deubiquitination Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Female Gamete Generation Protein Modification By Small Protein Removal Spermatid Development Cell Maturation Spermatid Differentiation	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Stem Cell Differentiation Catabolic Process Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phospholipid Scrambling Regulation Of Epithelial To Mesenchymal Transition Metabolic Process Endomembrane System Organization Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Phospholipid Transport Carboxylic Acid Catabolic Process Negative Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Programmed Cell Death Dopamine Metabolic Process Regulation Of Protein Autophosphorylation Positive Regulation Of Homocysteine Metabolic Process RRNA Base Methylation Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutaminyl-tRNA Aminoacylation Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport UDP-glucose Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To Phosphate Starvation Male Meiosis Chromosome Separation Regulation Of Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Phosphorylation Protein Ubiquitination Regulation Of Apoptotic Process
Tagcloud ?		adenocarcinoma autophagic autophagosome autophagy blocking coexist compartment cooperate correspondingly ductal engineered facilitating inactivation link localizing lysosomal lysosome machinery maintaining mechanistic mediators oncogenic pancreatic pda potently ras reprogramming suppresses synergistically	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Difference) ?		adenocarcinoma autophagic autophagosome autophagy blocking coexist compartment cooperate correspondingly ductal engineered facilitating inactivation link localizing lysosomal lysosome machinery maintaining mechanistic mediators oncogenic pancreatic pda potently ras reprogramming suppresses synergistically	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Intersection) ?