GCA and MAGEA8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GCA	MAGEA8
Description		grancalcin	MAGE family member A8
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome	Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Membrane Fusion	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Neutrophil degranulation
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 CALCOCO2 CSTPP1 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3	15 interacting genes: BEX5 CCDC59 GCA LMO2 LXN MAGEB4 MLH1 MTUS2 PKD2 TDRD7 UBE3A WT1 ZNF221 ZNF224 ZNF417
Entrez ID		25801	4107
HPRD ID		06122	02278
Ensembl ID		ENSG00000115271	ENSG00000156009
Uniprot IDs		B7Z322 H7BXD5 P28676	B2R9W4 P43361
PDB IDs		1F4O 1F4Q 1K94 1K95	8FJB
Enriched GO Terms of Interacting Partners?		Thioesterase Binding	Metanephric S-shaped Body Morphogenesis S-shaped Body Morphogenesis Metanephric Mesenchyme Development Metanephric Epithelium Development Renal Tubule Morphogenesis Regulation Of Transcription By RNA Polymerase II Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Branching Involved In Ureteric Bud Morphogenesis Metanephric Cortical Collecting Duct Development Metanephric Cortex Development Metanephric Distal Tubule Development Mesonephric Epithelium Development Mesonephric Tubule Development Sperm Entry Positive Regulation Of Golgi Lumen Acidification Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Polycystin Complex Metanephric Smooth Muscle Tissue Development Cellular Response To CAMP Mesenchyme Development Renal Artery Morphogenesis Kidney Epithelium Development Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Male Meiosis Chromosome Segregation MutLalpha Complex Cellular Response To Hydrostatic Pressure Detection Of Nodal Flow Regulation Of Golgi Lumen Acidification Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Response To CAMP Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Guanine/thymine Mispair Binding Homologous Chromosome Segregation
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