PCM1 and CEP131

Number of citations of the paper that reports this interaction (PMID 24121310)
4

Data Source:
BioGRID (pull down)

		PCM1	CEP131
Gene Name		pericentriolar material 1	centrosomal protein 131kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Cytosol Membrane Nonmotile Primary Cilium Nuclear Membrane Centriolar Satellite Ciliary Basal Body Protein Complex	Acrosomal Vesicle Nucleus Nucleoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Microtubule Cytoskeleton Nuclear Membrane Centriolar Satellite Cell Projection Intracellular Membrane-bounded Organelle Intercellular Bridge
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function Protein Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Negative Regulation Of Neurogenesis Centrosome Organization Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Maintenance	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Multicellular Organismal Development Spermatogenesis Positive Regulation Of Cell Proliferation Regulation Of Centrosome Duplication Cell Differentiation Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Intracellular Protein Transport
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Economic and political preferences ( 22566634)
Protein-Protein Interactions		17 interactors: ABI2 BBS4 CASK CCDC53 CEP131 CEP72 E2F4 EPS8 EXOC8 HAP1 ING5 KIAA0368 KRT15 KRT19 PCNT TTC8 YWHAQ	2 interactors: MIB1 PCM1
Entrez ID		5108	22994
HPRD ID		02624	16532
Ensembl ID		ENSG00000078674	ENSG00000141577
Uniprot IDs		A2RUU9 E7ETA6 Q15154	I3L2J8 Q9UPN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cilium Organization Cilium Morphogenesis Mitotic Cell Cycle Positive Regulation Of Cilium Assembly Sensory Processing Cell Cycle Process Mitotic Cell Cycle Process Cilium Assembly Cell Projection Organization Microtubule-based Process Organelle Assembly Cell Cycle Regulation Of Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Projection Assembly Regulation Of Microtubule-based Movement Cellular Protein Complex Localization Rac Protein Signal Transduction Organ Development Nonmotile Primary Cilium Assembly G2/M Transition Of Mitotic Cell Cycle Cytoskeleton Organization Protein Complex Localization Anatomical Structure Development Regulation Of Cilium Assembly Positive Regulation Of Transport Positive Regulation Of Organelle Assembly Brain Development Positive Regulation Of Organelle Organization Cellular Component Assembly Head Development Regulation Of Intracellular Transport Cell Projection Morphogenesis Regulation Of Microtubule-based Process Forebrain Development Cell Part Morphogenesis Developmental Process Movement Of Cell Or Subcellular Component Olfactory Bulb Development Brain Morphogenesis Central Nervous System Development Multicellular Organismal Development Olfactory Lobe Development Eye Photoreceptor Cell Differentiation Positive Regulation Of Intracellular Transport Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Positive Regulation Of Neurotrophin Production	Negative Regulation Of Neurogenesis Negative Regulation Of Cell Development Intraciliary Transport Involved In Cilium Morphogenesis Microtubule Anchoring At Centrosome Regulation Of Neurogenesis Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Cell Differentiation Positive Regulation Of Transport Protein Localization To Centrosome Regulation Of Cell Development Interkinetic Nuclear Migration Protein Localization To Cytoskeleton Neuronal Stem Cell Maintenance Anatomical Structure Formation Involved In Morphogenesis Intraciliary Transport Cytoplasmic Microtubule Organization Nucleus Localization Cell Proliferation In Forebrain Generation Of Neurons Regulation Of Cell Differentiation Microtubule Anchoring Neurogenesis Heart Looping Determination Of Heart Left/right Asymmetry Embryonic Heart Tube Morphogenesis Somitogenesis Embryonic Heart Tube Development Somite Development Centrosome Organization Positive Regulation Of Endocytosis Neural Precursor Cell Proliferation Determination Of Left/right Symmetry Microtubule Organizing Center Organization Nervous System Development Determination Of Bilateral Symmetry Segmentation G2/M Transition Of Mitotic Cell Cycle Anatomical Structure Morphogenesis Neural Tube Formation Microtubule-based Transport Notch Signaling Pathway Cytoskeleton-dependent Intracellular Transport Maintenance Of Protein Location In Cell Embryonic Epithelial Tube Formation Epithelial Tube Formation Maintenance Of Protein Location Stem Cell Maintenance Maintenance Of Location In Cell Positive Regulation Of Intracellular Protein Transport Tube Formation
Tagcloud ?		9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib termed usually
Tagcloud (Difference) ?		9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib termed usually
Tagcloud (Intersection) ?