SLC35H1 and TMEM14B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35H1	TMEM14B
Description		solute carrier family 35 member H1	transmembrane protein 14B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Antiporter Activity	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Fucosylation Protein O-linked Glycosylation Via Fucose Positive Regulation Of Notch Signaling Pathway	Heme Biosynthetic Process Nervous System Development Cerebral Cortex Development Neural Precursor Cell Proliferation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		123 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD APOL2 APOL3 ARL6IP1 ARLN ASGR1 ATP13A1 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C1GALT1 C2 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYB5B CYBC1 DNAJC30 EFNA5 EMC6 EMD EMP3 FA2H FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GOSR2 GPR152 IGFBP5 INSIG2 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NINJ2 NKG7 NRM ORMDL1 ORMDL2 ORMDL3 PDCD1LG2 PEX16 PLLP PLN PLP1 PLP2 PNLIPRP1 PRB1 RTP2 RUSF1 SACM1L SCD SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A7 SLC30A3 SLC35F1 SLC38A7 SLC66A1 SMCO4 SSMEM1 STATH STRIT1 STX3 STX8 SYNDIG1 SYS1 TAP1 TECR TF THBD TMEM107 TMEM120B TMEM128 TMEM147 TMEM14A TMEM14B TMEM14C TMEM239 TMEM31 TMEM50B TMEM60 TMEM65 TMEM86A TMEM97 TPRG1 TSNARE1 TSPAN2 TSPAN33 TSPO2 TVP23B UNC93B1 UPK1B VAMP4 VEGFA VTI1B YIF1A YIPF4 YIPF6	235 interacting genes: ABHD16A ABHD5 ACSL5 ADAM33 AGPAT3 AGPAT4 AGR3 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARL8B ARV1 ATP13A1 B4GALT7 BIK BLCAP BMP10 BSG BTN2A2 C10orf67 C14orf180 C1GALT1 C2CD2L CCL4 CD79A CEPT1 CFHR5 CIDEB CLDN10 CLDND2 CMTM5 CMTM8 CNIH2 CNIH3 CNIH4 COMT CPLX4 CREB3 CREB3L1 CXCL16 CYB561 CYB5R3 DEFB103A DEFB103B DGAT2L6 DHRSX EBP EI24 EMC6 EPHX4 ERGIC3 EXTL1 FA2H FADS6 FAM209A FCER1G FHL3 FIS1 FKBP8 FUNDC2 FXYD6-FXYD2 GDAP1 GIMAP1 GPR152 GPX8 GYPA GYPC HEXB HIBADH HIGD1C HMOX1 HMOX2 HSD17B11 HSD17B13 HSD3B1 IER3IP1 IFITM3 INSIG2 ITGAM JAGN1 KCNA1 KCNK1 KHDRBS2 LEPROTL1 LMNA LPAR3 LRCH1 MAL2 MARCHF5 MEOX2 MFSD12 MGAM MID2 MMD2 MS4A13 MS4A4A NAT8 NCALD NDUFA3 NEU1 NINJ1 NINJ2 NIPAL3 ORMDL1 OTULINL PAGE1 PDPN PDZK1IP1 PEX11G PIGF PLLP PLP1 PLP2 PMP22 PNLIPRP1 PPP2R3B PRAF2 PRH1 PRTFDC1 PSMD3 PTPMT1 RABAC1 REEP4 RHD RHOT2 SAR1B SCAMP5 SCN3B SCRG1 SERF1A SERF1B SERP1 SERP2 SFT2D1 SFT2D2 SFXN1 SFXN2 SFXN3 SLC10A6 SLC16A10 SLC16A13 SLC18A1 SLC19A3 SLC2A6 SLC30A3 SLC30A8 SLC35A4 SLC35E3 SLC35E4 SLC35F1 SLC35F6 SLC35G1 SLC35H1 SLC39A2 SLC39A7 SLC48A1 SLC61A1 SLC7A8 SMAGP SMPD2 SPRY2 SQLE ST6GAL2 STOM STX12 STX3 STX6 STX8 SUCNR1 SYNGR1 SYNJ2BP TAP1 TAS2R19 TBC1D20 TEX44 THBD TIMM22 TIMM23 TIMMDC1 TLCD1 TM4SF4 TMEM11 TMEM120A TMEM120B TMEM121 TMEM147 TMEM14A TMEM14C TMEM187 TMEM19 TMEM203 TMEM220 TMEM222 TMEM229B TMEM243 TMEM254 TMEM255B TMEM267 TMEM42 TMEM50A TMEM50B TMEM51 TMEM60 TMEM69 TMEM97 TMIE TMUB1 TMX2 TOMM6 TSPAN2 TSPO TVP23B UBE2J1 UBE2J2 UBE3A UBIAD1 UBXN8 UNC50 UNC93A VAMP1 VAMP5 VMA12 VRK2 VTI1B YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC11 ZDHHC22 ZDHHC24 ZFPL1
Entrez ID		51006	81853
HPRD ID		15371	15523
Ensembl ID		ENSG00000080189	ENSG00000137210
Uniprot IDs		B7Z6R4 Q9NQQ7	A0A087WU83 C9JCY4 C9JQS0 Q9NUH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Cellular Localization Structural Constituent Of Myelin Sheath Protein Binding Endomembrane System SNARE Complex Myelination Axon Ensheathment Membrane Fusion Golgi Membrane Intracellular Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Establishment Of Protein Localization Membrane Organization Organelle Fusion Golgi Vesicle Transport Negative Regulation Of Sphingolipid Biosynthetic Process Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Establishment Of Localization In Cell Vesicle Fusion With Golgi Apparatus Serine Palmitoyltransferase Complex Establishment Of Protein Localization To Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Positive Regulation Of Transport Lipid Biosynthetic Process Chemical Homeostasis Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Presynaptic Endosome Membrane Regulation Of Transport Protein Transport SNARE Binding Localization Within Membrane Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Respiratory Burst After Phagocytosis Regulation Of Membrane Lipid Metabolic Process Regulation Of Cellular Localization Membrane Docking Cholesterol Binding Vesicle Organization Lipid Metabolic Process Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Endomembrane System Golgi Apparatus Lipid Biosynthetic Process Membrane Organization Cellular Localization Transmembrane Transport Golgi Membrane Mitochondrial Outer Membrane Transmembrane Transporter Activity Vesicle-mediated Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Establishment Of Protein Localization Serine Import Into Mitochondrion Organic Cation Transport SNARE Complex Structural Constituent Of Myelin Sheath Mitochondrial Membrane SNAP Receptor Activity Organelle Fusion Monoatomic Ion Transmembrane Transporter Activity Steroid Biosynthetic Process Amino Acid Transport Myelination Axon Ensheathment Vesicle Fusion Organic Hydroxy Compound Transport Organelle Membrane Fusion Lipid Homeostasis Heme Metabolic Process Pigment Metabolic Process Cholesterol Biosynthetic Process Golgi Trans Cisterna Import Into The Mitochondrion COPII-coated ER To Golgi Transport Vesicle Lipid Metabolic Process Heme Oxidation Heme Oxygenase (decyclizing) Activity Amino Acid Transmembrane Transport Golgi Medial Cisterna SNARE Binding Zinc Ion Transmembrane Transporter Activity Sterol Biosynthetic Process Serine Transport Porphyrin-containing Compound Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Chemical Homeostasis
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