SLC35H1 and SLC35F1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35H1	SLC35F1
Description		solute carrier family 35 member H1	solute carrier family 35 member F1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse
	Molecular Function	Protein Binding Antiporter Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Fucosylation Protein O-linked Glycosylation Via Fucose Positive Regulation Of Notch Signaling Pathway	Transmembrane Transport
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737 29892015 28416818) Cardiac structure and function ( 19584346) Diastolic blood pressure ( 27841878 28135244) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate ( 23583979) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Left ventricular global longitudinal strain ( 33495596) PR interval ( 32439900) QRS duration ( 27659466 30679814) QT interval ( 29213071 29874175 30679814 24952745 19587794 19305408) Resting heart rate ( 20639392) Systolic blood pressure ( 27841878) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) TPE interval (resting) ( 32386560)
Interacting Genes		123 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD APOL2 APOL3 ARL6IP1 ARLN ASGR1 ATP13A1 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C1GALT1 C2 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYB5B CYBC1 DNAJC30 EFNA5 EMC6 EMD EMP3 FA2H FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GOSR2 GPR152 IGFBP5 INSIG2 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NINJ2 NKG7 NRM ORMDL1 ORMDL2 ORMDL3 PDCD1LG2 PEX16 PLLP PLN PLP1 PLP2 PNLIPRP1 PRB1 RTP2 RUSF1 SACM1L SCD SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A7 SLC30A3 SLC35F1 SLC38A7 SLC66A1 SMCO4 SSMEM1 STATH STRIT1 STX3 STX8 SYNDIG1 SYS1 TAP1 TECR TF THBD TMEM107 TMEM120B TMEM128 TMEM147 TMEM14A TMEM14B TMEM14C TMEM239 TMEM31 TMEM50B TMEM60 TMEM65 TMEM86A TMEM97 TPRG1 TSNARE1 TSPAN2 TSPAN33 TSPO2 TVP23B UNC93B1 UPK1B VAMP4 VEGFA VTI1B YIF1A YIPF4 YIPF6	7 interacting genes: AQP6 COMT GJA5 GJA8 SLC35H1 TMEM14B TRARG1
Entrez ID		51006	222553
HPRD ID		15371	18751
Ensembl ID		ENSG00000080189	ENSG00000196376
Uniprot IDs		B7Z6R4 Q9NQQ7	Q5T1Q4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Cellular Localization Structural Constituent Of Myelin Sheath Protein Binding Endomembrane System SNARE Complex Myelination Axon Ensheathment Membrane Fusion Golgi Membrane Intracellular Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Establishment Of Protein Localization Membrane Organization Organelle Fusion Golgi Vesicle Transport Negative Regulation Of Sphingolipid Biosynthetic Process Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Establishment Of Localization In Cell Vesicle Fusion With Golgi Apparatus Serine Palmitoyltransferase Complex Establishment Of Protein Localization To Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Positive Regulation Of Transport Lipid Biosynthetic Process Chemical Homeostasis Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Presynaptic Endosome Membrane Regulation Of Transport Protein Transport SNARE Binding Localization Within Membrane Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Respiratory Burst After Phagocytosis Regulation Of Membrane Lipid Metabolic Process Regulation Of Cellular Localization Membrane Docking Cholesterol Binding Vesicle Organization Lipid Metabolic Process Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Transmembrane Transport Renal System Process Gap Junction Channel Activity Connexin Complex Gap Junction Nitrate Transmembrane Transporter Activity Norepinephrine Secretion Catechol O-methyltransferase Activity Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Phosphate Starvation Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Membrane Habituation Cell-cell Signaling Mastication Blood Vessel Development Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream Signaling Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling Regulation Of Renin Secretion Into Blood Stream SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Regulation Of AV Node Cell Action Potential UDP-glucose Transmembrane Transport Carbon Dioxide Transmembrane Transporter Activity
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