SLC35H1 and SSMEM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35H1	SSMEM1
Description		solute carrier family 35 member H1	serine rich single-pass membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Membrane
	Molecular Function	Protein Binding Antiporter Activity	Protein Binding
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Fucosylation Protein O-linked Glycosylation Via Fucose Positive Regulation Of Notch Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		123 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD APOL2 APOL3 ARL6IP1 ARLN ASGR1 ATP13A1 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C1GALT1 C2 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYB5B CYBC1 DNAJC30 EFNA5 EMC6 EMD EMP3 FA2H FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GOSR2 GPR152 IGFBP5 INSIG2 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NINJ2 NKG7 NRM ORMDL1 ORMDL2 ORMDL3 PDCD1LG2 PEX16 PLLP PLN PLP1 PLP2 PNLIPRP1 PRB1 RTP2 RUSF1 SACM1L SCD SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A7 SLC30A3 SLC35F1 SLC38A7 SLC66A1 SMCO4 SSMEM1 STATH STRIT1 STX3 STX8 SYNDIG1 SYS1 TAP1 TECR TF THBD TMEM107 TMEM120B TMEM128 TMEM147 TMEM14A TMEM14B TMEM14C TMEM239 TMEM31 TMEM50B TMEM60 TMEM65 TMEM86A TMEM97 TPRG1 TSNARE1 TSPAN2 TSPAN33 TSPO2 TVP23B UNC93B1 UPK1B VAMP4 VEGFA VTI1B YIF1A YIPF4 YIPF6	99 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ARLN ATP6V0C BET1 BLCAP C11orf24 C1QL4 C5 CCL4L2 CDIPT CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 JAGN1 LAT LEPROTL1 LHFPL5 LNPEP MARCHF2 MCRS1 MFSD12 MFSD6 MIP MMD2 MS4A13 NINJ2 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35E3 SLC35H1 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC61A1 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1
Entrez ID		51006	136263
HPRD ID		15371	14060
Ensembl ID		ENSG00000080189	ENSG00000165120
Uniprot IDs		B7Z6R4 Q9NQQ7	A0A3B3ISA2 Q8WWF3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Cellular Localization Structural Constituent Of Myelin Sheath Protein Binding Endomembrane System SNARE Complex Myelination Axon Ensheathment Membrane Fusion Golgi Membrane Intracellular Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Establishment Of Protein Localization Membrane Organization Organelle Fusion Golgi Vesicle Transport Negative Regulation Of Sphingolipid Biosynthetic Process Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Establishment Of Localization In Cell Vesicle Fusion With Golgi Apparatus Serine Palmitoyltransferase Complex Establishment Of Protein Localization To Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Positive Regulation Of Transport Lipid Biosynthetic Process Chemical Homeostasis Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Presynaptic Endosome Membrane Regulation Of Transport Protein Transport SNARE Binding Localization Within Membrane Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Respiratory Burst After Phagocytosis Regulation Of Membrane Lipid Metabolic Process Regulation Of Cellular Localization Membrane Docking Cholesterol Binding Vesicle Organization Lipid Metabolic Process Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Water Channel Activity Phosphatidate Phosphatase Activity Transmembrane Transport Glycerol Transmembrane Transport Carbohydrate Transport Water Transport Polyol Transmembrane Transport Phospholipid Metabolic Process Alkenylglycerophosphocholine Hydrolase Activity Fluid Transport Phospholipid Dephosphorylation Plasma Membrane Channel Activity Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Diacylglycerol Diphosphate Phosphatase Activity Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Magnesium Ion Transport Carbohydrate Transmembrane Transport Amide Transport Glycerol Channel Activity Lipid Phosphatase Activity Renal Water Absorption One-carbon Compound Transport Urea Transmembrane Transporter Activity Farnesyl Diphosphate Metabolic Process Gap Junction-mediated Intercellular Transport Sphingosine-1-phosphate Phosphatase Activity CCR6 Chemokine Receptor Binding Antigen Processing And Presentation Of Peptide Antigen Response To Bacterium Chemotaxis Lysophosphatidic Acid Phosphatase Activity Inorganic Cation Transmembrane Transporter Activity Renal Water Transport Neutrophil Differentiation Glutamine Transport L-glutamine Transmembrane Transporter Activity Locomotion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Ammonium Channel Activity Urea Transmembrane Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
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