HOXB8

Description		homeobox B8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Grooming Behavior Adult Locomotory Behavior Anterior/posterior Pattern Specification Sensory Perception Of Pain Dorsal Spinal Cord Development Negative Regulation Of Myeloid Cell Differentiation Embryonic Skeletal System Morphogenesis Skeletal System Morphogenesis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: MEIS1 OTUD3 PBX1 PBX2 PBX3
Entrez ID		3218
HPRD ID		00851
Ensembl ID		ENSG00000120068
Uniprot IDs		P17481 Q8N8T3
PDB IDs
Enriched GO Terms of Interacting Partners?		Eye Development Sensory Organ Development Transcription Regulator Complex Brain Development Pattern Specification Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Animal Organ Morphogenesis Embryonic Organ Development Neuron Development Proximal/distal Pattern Formation Cell Development Regionalization Regulation Of Transcription By RNA Polymerase II Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Regulation Of RNA Biosynthetic Process Animal Organ Development Negative Regulation Of Neuron Differentiation Anatomical Structure Morphogenesis Embryonic Limb Morphogenesis Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Limb Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein K6-linked Deubiquitination Anterior/posterior Pattern Specification DNA Binding Hemopoiesis DNA-binding Transcription Factor Binding Compartment Pattern Specification Protein K27-linked Deubiquitination Locomotory Behavior Regulation Of Neuron Differentiation Dorsal Spinal Cord Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Cell Growth Involved In Cardiac Muscle Cell Development
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