PAX7 and HIRA

Number of citations of the paper that reports this interaction (PMID 9731536)
29

Data Source:
HPRD (in vitro, two hybrid)

		PAX7	HIRA
Gene Name		paired box 7	histone cell cycle regulator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm PML Body Protein Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Chromatin Remodeling Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Regulation Of Cell Fate Commitment Skeletal Muscle Satellite Cell Commitment Spinal Cord Association Neuron Differentiation Dorsal/ventral Neural Tube Patterning Positive Regulation Of Histone Methylation Negative Regulation Of Apoptotic Process Regulation Of Protein Binding Skeletal Muscle Tissue Regeneration Positive Regulation Of Transcription From RNA Polymerase II Promoter Neuron Fate Commitment Embryonic Skeletal System Development Cartilage Development Muscle Tissue Morphogenesis Positive Regulation Of Myoblast Proliferation	Osteoblast Differentiation DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Gastrulation Anatomical Structure Morphogenesis Chromatin Modification Muscle Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		Body mass index ( 23669352) Orofacial clefts ( 22863734) Response to amphetamines ( 22952603)
Protein-Protein Interactions		1 interactors: HIRA	15 interactors: ASF1A ASF1B CCNA2 CDK2 H3F3B HIRIP3 HIST1H2BD HIST1H2BK HIST2H2BE HNRNPD NFU1 PAX7 SUMO1 UBN1 UPF1
Entrez ID		5081	7290
HPRD ID		01331	02583
Ensembl ID		ENSG00000009709	ENSG00000100084
Uniprot IDs		P23759	P54198
PDB IDs			2I32
Enriched GO Terms of Interacting Partners?			Chromatin Organization Chromosome Organization Chromatin Assembly Or Disassembly DNA Replication-independent Nucleosome Assembly Nucleosome Assembly Organelle Organization Chromatin Assembly Nucleosome Organization Protein-DNA Complex Assembly DNA Packaging DNA Conformation Change DNA Replication-dependent Nucleosome Assembly Chromatin Modification Cellular Macromolecular Complex Assembly Innate Immune Response In Mucosa Response To Stress Regulation Of Gene Silencing Cellular Response To DNA Damage Stimulus Antibacterial Humoral Response Regulation Of Gene Expression Antimicrobial Humoral Response Mucosal Immune Response Regulation Of Gene Expression, Epigenetic Protein Complex Assembly Regulation Of Transcription, DNA-templated DNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Repair Regulation Of RNA Metabolic Process Cellular Component Assembly Skeletal Muscle Satellite Cell Commitment Regulation Of Cellular Protein Metabolic Process Defense Response To Gram-positive Bacterium Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Mitotic DNA Integrity Checkpoint Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process PML Body Organization Positive Regulation Of DNA-dependent DNA Replication Initiation G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Localization To Nuclear Pore Positive Regulation Of Myoblast Proliferation
Tagcloud ?		6ped activators alveolar arms chimeric chromosomal copies cotransfected diphtheria effort exploit fkhr harbor lacks p36 pa3 pax3 plasmid plasmids prs q14 q35 rearrangements rhabdomyosarcoma sorting stably toxin transfections translocations	actively cabin1 caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Difference) ?		6ped activators alveolar arms chimeric chromosomal copies cotransfected diphtheria effort exploit fkhr harbor lacks p36 pa3 pax3 plasmid plasmids prs q14 q35 rearrangements rhabdomyosarcoma sorting stably toxin transfections translocations	actively cabin1 caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Intersection) ?