GPR143 and SUCLG2

Number of citations of the paper that reports this interaction (PMID 10471510)
28

Data Source:
HPRD (in vitro, in vivo)

		GPR143	SUCLG2
Gene Name		G protein-coupled receptor 143	succinate-CoA ligase, GDP-forming, beta subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane Melanosome Membrane Melanosome	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex (GDP-forming)
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding Dopamine Binding L-DOPA Receptor Activity L-DOPA Binding Tyrosine Binding	Succinate-CoA Ligase (GDP-forming) Activity ATP Binding GTP Binding GDP Binding Protein Heterodimerization Activity
	Biological Process	Eye Pigment Biosynthetic Process Signal Transduction G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Visual Perception Melanosome Localization Melanosome Transport Melanosome Organization Calcium-mediated Signaling Using Intracellular Calcium Source Phosphatidylinositol-mediated Signaling Regulation Of Calcium-mediated Signaling	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs			Succinic acid
Diseases
GWAS		Prostate cancer ( 23535732)	Corneal astigmatism ( 22144915) Height ( 20881960) IgE levels ( 23146381)
Protein-Protein Interactions		2 interactors: GNAI1 SUCLG2	2 interactors: GPR143 SUCLG1
Entrez ID		4935	8801
HPRD ID		02355	06799
Ensembl ID		ENSG00000101850	ENSG00000172340
Uniprot IDs		P51810	E9PDQ8 Q96I99
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinyl-CoA Metabolic Process Succinate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Vesicle Fusion Tricarboxylic Acid Metabolic Process Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Aerobic Respiration Acyl-CoA Metabolic Process Organelle Fusion Dicarboxylic Acid Metabolic Process Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Membrane Fusion	Eye Pigment Biosynthetic Process Succinyl-CoA Metabolic Process Eye Pigmentation Succinate Metabolic Process Calcium-mediated Signaling Using Intracellular Calcium Source Melanosome Organization Pigment Granule Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Tricarboxylic Acid Cycle Regulation Of Calcium-mediated Signaling Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Cellular Pigmentation Pigment Biosynthetic Process Aerobic Respiration Acyl-CoA Metabolic Process Developmental Pigmentation Calcium-mediated Signaling Neuropeptide Signaling Pathway Dicarboxylic Acid Metabolic Process Pigmentation Phosphatidylinositol-mediated Signaling Second-messenger-mediated Signaling Cellular Respiration Visual Perception Sensory Perception Of Light Stimulus Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization
Tagcloud ?		abrogation albinism autosomal biosynthesis clue computational confirms create enrichment eye hypopigmentation lab melanin mirna oa oca oca2 ocular oculocutaneous pigmentation reason recessive researches slc45a2 snps tyr tyrp1 utr wet
Tagcloud (Difference) ?		abrogation albinism autosomal biosynthesis clue computational confirms create enrichment eye hypopigmentation lab melanin mirna oa oca oca2 ocular oculocutaneous pigmentation reason recessive researches slc45a2 snps tyr tyrp1 utr wet
Tagcloud (Intersection) ?