NTSR1 and NTS

Number of citations of the paper that reports this interaction (PubMedID 11559354)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		NTSR1	NTS
Description		neurotensin receptor 1	neurotensin
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Membrane Axon Dendrite Symmetric Synapse Neuronal Cell Body Terminal Bouton Dendritic Spine Dendritic Shaft Perikaryon Axon Terminus Neuron Spine Membrane Raft	Extracellular Region Transport Vesicle Cytoplasmic Vesicle Axon Terminus
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Neurotensin Receptor Activity Identical Protein Binding Protein-containing Complex Binding	Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Neuropeptide Receptor Binding
	Biological Process	Temperature Homeostasis Negative Regulation Of Systemic Arterial Blood Pressure Regulation Of Membrane Depolarization CAMP Biosynthetic Process Response To Stress Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Learning Associative Learning Adult Locomotory Behavior Positive Regulation Of Gene Expression Positive Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Response To Food Regulation Of Inositol Trisphosphate Biosynthetic Process Response To Lipid Positive Regulation Of Locomotion Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Respiratory Gaseous Exchange Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Inositol Phosphate Biosynthetic Process D-aspartate Import Across Plasma Membrane Inositol Phosphate Catabolic Process Vocalization Behavior Positive Regulation Of Arachidonate Secretion Positive Regulation Of Inhibitory Postsynaptic Potential L-glutamate Import Across Plasma Membrane Conditioned Place Preference Regulation Of Behavioral Fear Response	Signal Transduction Neuropeptide Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Killing Of Cells Of Another Organism Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Blood Vessel Diameter Maintenance
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Metabolite levels ( 23823483)	Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: ARRB2 NTS	10 interacting genes: ACE2 ARRB2 CPE MEP1A MFF NLN NTSR1 NTSR2 PREP SORT1
Entrez ID		4923	4922
HPRD ID		01218	08878
Ensembl ID		ENSG00000101188	ENSG00000133636
Uniprot IDs		P30989	P30990 Q6FH20
PDB IDs		2LYW 6OS9 6OSA 6PWC 6UP7 7UL2 8JPB 8JPC 8JPF	2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ 6UP7 8VJY
Enriched GO Terms of Interacting Partners?		Protein Kinase B Binding Regulation Of Interleukin-12 Production Canonical NF-kappaB Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Angiotensin Receptor Binding Regulation Of Interleukin-6 Production Regulation Of Protein Ubiquitination Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Gene Expression Regulation Of Lymphocyte Mediated Immunity Neuropeptide Receptor Binding Protein-macromolecule Adaptor Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Post-translational Protein Modification Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication D1 Dopamine Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Signaling Regulation Of Canonical NF-kappaB Signal Transduction Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Interleukin-17A-mediated Signaling Pathway Regulation Of Synaptic Transmission, Dopaminergic Interleukin-33-mediated Signaling Pathway DNA-templated Transcription Enzyme Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Innate Immune Response Positive Regulation Of MAPK Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of Cardiac Muscle Cell Differentiation CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD40 Receptor Complex Positive Regulation Of JUN Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway T-helper 1 Type Immune Response Interleukin-17-mediated Signaling Pathway G Protein-coupled Receptor Internalization Negative Regulation Of Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Cardiocyte Differentiation MyD88-dependent Toll-like Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity	Peptide Hormone Processing Signaling Receptor Ligand Precursor Processing Neuropeptide Signaling Pathway Metallocarboxypeptidase Activity G Protein-coupled Neurotensin Receptor Activity Metallopeptidase Activity Hormone Metabolic Process Peptidase Activity Protein Processing Proteolysis Protein Maturation Angiotensin Maturation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Amino Acid Transport Carboxypeptidase Activity Regulation Of Biological Quality Regulation Of Hormone Levels Import Into Cell Peptide Metabolic Process Neurotensin Receptor Activity, Non-G Protein-coupled Plasma Membrane Endocytic Vesicle Membrane Angiotensin Receptor Binding Clathrin-coated Pit Adult Locomotory Behavior Cytoplasmic Vesicle Epidermal Growth Factor Receptor Ligand Maturation Meprin A Complex Inositol Phosphate Catabolic Process Regulation Of Amine Transport Oligopeptidase Activity Nerve Growth Factor Receptor Activity Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Regulation Of Striated Muscle Cell Differentiation Hydrolase Activity Metalloendopeptidase Activity Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Membrane Potential Membrane Protein Localization To Secretory Granule Positive Regulation Of Gamma-aminobutyric Acid Secretion Entry Receptor-mediated Virion Attachment To Host Cell Endocytosis Amino Acid Transport Symmetric Synapse Regulation Of Skeletal Muscle Fiber Differentiation Viral Translation Viral Life Cycle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?