NTS and NTSR2

Number of citations of the paper that reports this interaction (PubMedID 11801734)
0

Data Source:
HPRD (in vitro, in vivo)

		NTS	NTSR2
Description		neurotensin	neurotensin receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Transport Vesicle Cytoplasmic Vesicle Axon Terminus	Plasma Membrane Membrane
	Molecular Function	Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Neuropeptide Receptor Binding	G Protein-coupled Receptor Activity G Protein-coupled Neurotensin Receptor Activity
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Killing Of Cells Of Another Organism Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Blood Vessel Diameter Maintenance	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Sensory Perception Regulation Of Membrane Potential
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Levocabastine
Diseases
GWAS		Metabolite levels ( 23823483)	Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ACE2 ARRB2 CPE MEP1A MFF NLN NTSR1 NTSR2 PREP SORT1	1 interacting genes: NTS
Entrez ID		4922	23620
HPRD ID		08878	05704
Ensembl ID		ENSG00000133636	ENSG00000169006
Uniprot IDs		P30990 Q6FH20	O95665
PDB IDs		2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ 6UP7 8VJY
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Signaling Receptor Ligand Precursor Processing Neuropeptide Signaling Pathway Metallocarboxypeptidase Activity G Protein-coupled Neurotensin Receptor Activity Metallopeptidase Activity Hormone Metabolic Process Peptidase Activity Protein Processing Proteolysis Protein Maturation Angiotensin Maturation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Amino Acid Transport Carboxypeptidase Activity Regulation Of Biological Quality Regulation Of Hormone Levels Import Into Cell Peptide Metabolic Process Neurotensin Receptor Activity, Non-G Protein-coupled Plasma Membrane Endocytic Vesicle Membrane Angiotensin Receptor Binding Clathrin-coated Pit Adult Locomotory Behavior Cytoplasmic Vesicle Epidermal Growth Factor Receptor Ligand Maturation Meprin A Complex Inositol Phosphate Catabolic Process Regulation Of Amine Transport Oligopeptidase Activity Nerve Growth Factor Receptor Activity Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Regulation Of Striated Muscle Cell Differentiation Hydrolase Activity Metalloendopeptidase Activity Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Membrane Potential Membrane Protein Localization To Secretory Granule Positive Regulation Of Gamma-aminobutyric Acid Secretion Entry Receptor-mediated Virion Attachment To Host Cell Endocytosis Amino Acid Transport Symmetric Synapse Regulation Of Skeletal Muscle Fiber Differentiation Viral Translation Viral Life Cycle	Neuropeptide Receptor Binding
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