NTS and NTSR2

Number of citations of the paper that reports this interaction (PMID 16087676)
5

Data Source:
HPRD (in vivo, in vitro)

		NTS	NTSR2
Gene Name		neurotensin	neurotensin receptor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Transport Vesicle	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Neuropeptide Hormone Activity Protein Binding	G-protein Coupled Receptor Activity G-protein Coupled Neurotensin Receptor Activity
	Biological Process	Signal Transduction Regulation Of Blood Vessel Size	Cell Surface Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Sensory Perception Regulation Of Membrane Potential
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs			Levocabastine
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ACE2 ARRB2 CPE MEP1A NLN NTSR1 NTSR2 PREP SORT1	1 interactors: NTS
Entrez ID		4922	23620
HPRD ID		08878	05704
Ensembl ID		ENSG00000133636	ENSG00000169006
Uniprot IDs		P30990 Q6FH20	O95665
PDB IDs		2LNE 2LNF 2LNG 2LYW 3F6K
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Proteolysis G-protein Coupled Receptor Signaling Pathway Peptide Hormone Processing Receptor Metabolic Process Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Adult Locomotory Behavior Digestion Angiotensin-mediated Drinking Behavior Angiotensin Catabolic Process In Blood Behavior Peptide Metabolic Process Multicellular Organismal Protein Catabolic Process Adult Behavior Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Insulin Processing Negative Regulation Of Smooth Muscle Cell Apoptotic Process Multicellular Organismal Protein Metabolic Process Hormone Metabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Receptor Biosynthetic Process Drinking Behavior Virion Attachment To Host Cell Positive Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Lipoprotein Lipase Activity Plasma Membrane To Endosome Transport Cell Surface Receptor Signaling Pathway Glucose Import Brain Renin-angiotensin System Locomotory Behavior Protein Processing Insulin Metabolic Process Adhesion Of Symbiont To Host Cellular Amide Metabolic Process Regulation Of Hormone Levels Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Smooth Muscle Cell Apoptotic Process Peptide Catabolic Process Regulation Of Blood Volume By Renin-angiotensin G-protein Coupled Receptor Internalization Negative Regulation Of Interleukin-1 Beta Production Nerve Growth Factor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cardiac Left Ventricle Morphogenesis Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Synaptic Transmission, Dopaminergic	Regulation Of Blood Vessel Size Regulation Of Tube Size
Tagcloud ?		acts autocrine cascades competing directed document embedded gxkkxxk homopolymeric localizes mediator mid motif mutagenesis nucleolin nucleolus paracrine parathyroid predict preservation pthrp representing ribonucleoprotein rna rnas salt secreted shared translated
Tagcloud (Difference) ?		acts autocrine cascades competing directed document embedded gxkkxxk homopolymeric localizes mediator mid motif mutagenesis nucleolin nucleolus paracrine parathyroid predict preservation pthrp representing ribonucleoprotein rna rnas salt secreted shared translated
Tagcloud (Intersection) ?