VPS26C and MYRIP

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		VPS26C	MYRIP
Description		VPS26 endosomal protein sorting factor C	myosin VIIA and Rab interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome	Exocyst Photoreceptor Outer Segment Cytoplasm Cytosol Actin Cytoskeleton Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Cytoplasmic Vesicle Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Small GTPase Binding Metal Ion Binding Protein Kinase A Binding
	Biological Process	Intracellular Protein Transport Endocytic Recycling	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways			Insulin processing Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)
Interacting Genes		44 interacting genes: AGTPBP1 ARHGAP21 ASH1L CBLB CCDC85A CIPC DCLK1 DDIT4L DECR2 DNAJB2 EPHB6 INCA1 KIF1A KIF21A LRIF1 MAML3 MAPK6 MAPK8IP1 MDM4 MEI4 MEOX2 MRPS35 MYRIP NRCAM NSMF PALS2 PCM1 PEG10 PMS2 PRKD2 PTPN21 RAB39B RAP1GAP RAP1GAP2 SETMAR TAF1C TEPSIN TET2 TRAPPC1 U2AF1 VPS26A VPS35L XPA ZNF655	6 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B VPS26C
Entrez ID		10311	25924
HPRD ID		10390	14796
Ensembl ID		ENSG00000157538	ENSG00000170011
Uniprot IDs		A8MTY9 A8MY26 O14972	Q8NFW9
PDB IDs		8P0X 8SYN 8SYO 9AU7
Enriched GO Terms of Interacting Partners?			Melanosome Pigment Granule Localization Protein Domain Specific Binding Pigment Granule Transport Multivesicular Body Membrane Exocytic Vesicle Myosin V Binding Multivesicular Body Sorting Pathway Apical Plasma Membrane Vesicle-mediated Transport Upper Tip-link Density Protein Transport Myosin VII Complex Photoreceptor Outer Segment GDP Binding Positive Regulation Of Exocytosis Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway G Protein Activity Establishment Of Protein Localization Intracellular Protein Transport Establishment Of Vesicle Localization Secretory Granule Vesicle Localization Establishment Of Localization In Cell Complement-dependent Cytotoxicity Pericentric Heterochromatin Organization CENP-A Recruiting Complex Late Endosome Phagolysosome Assembly Stereocilium Base Intracellular Protein Localization Exosomal Secretion Endosome Equilibrioception Regulation Of Exocytosis Weibel-Palade Body Exocytosis Platelet Dense Granule Membrane Natural Killer Cell Degranulation Photoreceptor Cell Cilium Anterograde Axonal Protein Transport Establishment Of Organelle Localization CENP-A Containing Chromatin Assembly Chromocenter Positive Regulation Of Secretion By Cell Protein Transport Along Microtubule Vesicle Organization GTPase Activity Positive Regulation Of Secretion
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