VPS26C and SETMAR

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		VPS26C	SETMAR
Description		VPS26 endosomal protein sorting factor C	SET and mariner transposase domain methyltransferase
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GO Annotations	Cellular Component	Nucleus Endosome	Condensed Chromosome Nucleus Chromosome Nucleolus Site Of Double-strand Break
	Molecular Function	Protein Binding	Single-stranded DNA Endodeoxyribonuclease Activity Nucleic Acid Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Catalytic Activity Nuclease Activity Endonuclease Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Protein-lysine N-methyltransferase Activity Transferase Activity Hydrolase Activity Histone Methyltransferase Activity Histone H3K4 Methyltransferase Activity Protein Homodimerization Activity DNA Topoisomerase Binding Metal Ion Binding Histone H3K36 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K36 Dimethyltransferase Activity
	Biological Process	Intracellular Protein Transport Endocytic Recycling	DNA Double-strand Break Processing DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Catabolic Process Chromatin Organization Chromatin Remodeling DNA Damage Response Cell Population Proliferation DNA Integration Replication Fork Processing Methylation Mitotic DNA Integrity Checkpoint Signaling Nucleic Acid Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Chromosome Organization
Pathways
Drugs
Diseases
GWAS			Fractures (paediatric) ( 32742401) Midgestational circulating levels of PCBs ( 28235828) Periodontitis (DPAL) ( 24024966) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Spondylosis ( 33332786)
Interacting Genes		44 interacting genes: AGTPBP1 ARHGAP21 ASH1L CBLB CCDC85A CIPC DCLK1 DDIT4L DECR2 DNAJB2 EPHB6 INCA1 KIF1A KIF21A LRIF1 MAML3 MAPK6 MAPK8IP1 MDM4 MEI4 MEOX2 MRPS35 MYRIP NRCAM NSMF PALS2 PCM1 PEG10 PMS2 PRKD2 PTPN21 RAB39B RAP1GAP RAP1GAP2 SETMAR TAF1C TEPSIN TET2 TRAPPC1 U2AF1 VPS26A VPS35L XPA ZNF655	3 interacting genes: H3-5 PRPF19 VPS26C
Entrez ID		10311	6419
HPRD ID		10390	10225
Ensembl ID		ENSG00000157538	ENSG00000170364
Uniprot IDs		A8MTY9 A8MY26 O14972	B4DND2 Q53H47 Q96H41
PDB IDs		8P0X 8SYN 8SYO 9AU7	3BO5 3F2K 3K9J 3K9K 7S03
Enriched GO Terms of Interacting Partners?
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