NOV and ADSL

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NOV	ADSL
Gene Name		nephroblastoma overexpressed	adenylosuccinate lyase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Axon Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle	Cytosol
	Molecular Function	Integrin Binding Insulin-like Growth Factor Binding Growth Factor Activity Heparin Binding	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) Activity (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) Activity
	Biological Process	Regulation Of Cell Growth Cell Adhesion Signal Transduction Cell-cell Signaling Regulation Of Gene Expression Negative Regulation Of Cell Death	Purine Nucleobase Metabolic Process Purine Nucleotide Biosynthetic Process AMP Biosynthetic Process 'de Novo' IMP Biosynthetic Process Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process 'de Novo' AMP Biosynthetic Process Small Molecule Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs		Insulin Regular Insulin, porcine
Diseases
GWAS		Blood pressure ( 21909110) Hypertension ( 21626137)	Height ( 19570815)
Protein-Protein Interactions		14 interactors: ADSL CDKN1A CTGF DLL1 FBLN1 FN1 GJA1 IGF1 IGF2 INS ITGAV NOTCH1 POLR2L S100A4	3 interactors: CALCOCO2 NOV REL
Entrez ID		4856	158
HPRD ID		01291	00049
Ensembl ID		ENSG00000136999	ENSG00000239900
Uniprot IDs		P48745	E7ERF4 P30566
PDB IDs			2J91 2VD6 4FFX 4FLC
Enriched GO Terms of Interacting Partners?		Response To Wounding Wound Healing Regulation Of Growth Regulation Of Cell Differentiation Positive Regulation Of Glycogen Biosynthetic Process Developmental Process Tissue Development Positive Regulation Of Protein Metabolic Process Cell Development Cell Differentiation Positive Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Proliferation Regulation Of Cellular Component Organization Cardiovascular System Development Multicellular Organismal Development Vasculature Development Anatomical Structure Development Positive Regulation Of Cell Cycle Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Metabolic Process System Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Glycogen Metabolic Process Anatomical Structure Morphogenesis Digestive System Development Tube Development Positive Regulation Of Mitotic Nuclear Division Response To Stress Compartment Pattern Specification Blood Vessel Morphogenesis Tissue Regeneration Response To Organonitrogen Compound Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Heart Looping Response To Peptide Regulation Of Cell Cycle Process Enzyme Linked Receptor Protein Signaling Pathway Determination Of Heart Left/right Asymmetry Secretion By Cell Blood Vessel Development Embryonic Heart Tube Morphogenesis Organ Development
Tagcloud ?		autologous avian chicken cloned conserved element elements elevated encodes homolog igfii interrelated inversely kidney might nephroblastomas novh oncogene overexpressed predominantly proto putative relative represent sequenced stromal tumors wilms wt1	adsls allergen antiseptic atopic benzalkonium bzk chg chlorhexidine dermatitis diatheses dp ear envelope gluconate handlers ig ige immunoreaction iodine irritation mast mite nc nga povidone pvp subcutaneous subcutaneously w
Tagcloud (Difference) ?		autologous avian chicken cloned conserved element elements elevated encodes homolog igfii interrelated inversely kidney might nephroblastomas novh oncogene overexpressed predominantly proto putative relative represent sequenced stromal tumors wilms wt1	adsls allergen antiseptic atopic benzalkonium bzk chg chlorhexidine dermatitis diatheses dp ear envelope gluconate handlers ig ige immunoreaction iodine irritation mast mite nc nga povidone pvp subcutaneous subcutaneously w
Tagcloud (Intersection) ?