CCN3 and ZNF330

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCN3	ZNF330
Description		cellular communication network factor 3	zinc finger protein 330
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cytosol Gap Junction Extracellular Matrix Anchoring Junction	Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Cilium Midbody Ciliary Basal Body
	Molecular Function	Signaling Receptor Binding Notch Binding Integrin Binding Hormone Activity Protein Binding Growth Factor Activity Heparin Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Angiogenesis Chondrocyte Differentiation Cell Adhesion Signal Transduction Fibroblast Migration Negative Regulation Of Myotube Differentiation Smooth Muscle Cell Migration Negative Regulation Of Cell Growth Cell Adhesion Mediated By Integrin Endothelial Cell Chemotaxis Type B Pancreatic Cell Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Ossification Negative Regulation Of Insulin Secretion Smooth Muscle Cell Proliferation Negative Regulation Of Inflammatory Response Regulation Of Developmental Process Cell Chemotaxis Negative Regulation Of SMAD Protein Signal Transduction Hematopoietic Stem Cell Homeostasis Endothelial Cell-cell Adhesion Negative Regulation Of Monocyte Chemotaxis Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Sensory Perception Of Pain Bone Regeneration
Pathways
Drugs		Insulin human
Diseases
GWAS			Conduct disorder ( 20585324) Malaria ( 31844061)
Interacting Genes		31 interacting genes: ADSL ANKRD11 APOL6 C11orf87 CCN2 CDKN1A COL8A1 DLL1 FAM90A1 FBLN1 FN1 FRS3 FXR1 FXR2 GJA1 HOXA1 IGF1 IGF2 INS ITGAV KRTAP5-6 LCE1A LCE3D NID2 NOTCH1 POLR2L POU4F2 RECK S100A4 TNIP3 ZNF330	51 interacting genes: ADAMTSL4 CCDC33 CCN3 CFP CHIC2 CNNM3 CREB5 CYSRT1 KLF15 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP13-3 KRTAP5-7 MDFI MEOX2 NBPF19 NDUFB7 NOTCH2NLA NR4A3 OTX1 PBX4 PICK1 RBAK RSPO2 RSPO4 SPATA3 SPRY1 STK16 STX19 SUFU TCL1B TLE5 TRIM42 ZBTB42 ZNF23 ZNF250 ZNF408 ZNF426 ZNF440 ZNF460 ZNF547 ZNF587 ZNF655 ZNF664 ZNF669 ZNF683 ZNF688 ZNF764 ZNF768 ZNF837
Entrez ID		4856	27309
HPRD ID		01291	15775
Ensembl ID		ENSG00000136999	ENSG00000109445
Uniprot IDs		P48745	B4DFG9 Q53EN0 Q9Y3S2
PDB IDs
Enriched GO Terms of Interacting Partners?		Tissue Development Epidermis Development Integrin Binding Positive Regulation Of Growth Positive Regulation Of Developmental Growth Regulation Of Growth Regulation Of Developmental Growth Regulation Of Cell Differentiation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Fibroblast Proliferation Receptor Ligand Activity Insulin-like Growth Factor Receptor Binding Positive Regulation Of Glycogen Biosynthetic Process Wound Healing Positive Regulation Of Signal Transduction Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Regulation Of Cell Development Regulation Of Nervous System Development Insulin Receptor Binding Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Developmental Process Regulation Of Multicellular Organismal Process Negative Regulation Of Gene Expression Angiogenesis Positive Regulation Of Cell Differentiation Alphav-beta3 Integrin-IGF-1-IGF1R Complex Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Compartment Pattern Specification Positive Regulation Of Intracellular Signal Transduction Regulation Of Fibroblast Proliferation Regulation Of Glycogen Biosynthetic Process Basement Membrane Negative Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Response To Wounding Extracellular Region Positive Regulation Of Cell Communication Positive Regulation Of Signaling Integrin-mediated Signaling Pathway Positive Regulation Of Skeletal Muscle Tissue Growth Endodermal Cell Differentiation Positive Regulation Of D-glucose Import Cell-matrix Adhesion Regulation Of Neurogenesis Regulation Of Glycogen Metabolic Process Regulation Of Somitogenesis Positive Regulation Of Neurogenesis Regulation Of Skeletal Muscle Tissue Growth	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Zinc Ion Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Intermediate Filament Sequence-specific Double-stranded DNA Binding Protein Binding Regulation Of Macromolecule Metabolic Process Limb Development CAMP Response Element Binding DNA-binding Transcription Factor Activity Golgi-associated Vesicle
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