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CCN3
Description
cellular communication network factor 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Cytosol
Gap Junction
Extracellular Matrix
Anchoring Junction
Molecular Function
Signaling Receptor Binding
Notch Binding
Integrin Binding
Hormone Activity
Protein Binding
Growth Factor Activity
Heparin Binding
Biological Process
Angiogenesis
Chondrocyte Differentiation
Cell Adhesion
Signal Transduction
Fibroblast Migration
Negative Regulation Of Myotube Differentiation
Smooth Muscle Cell Migration
Negative Regulation Of Cell Growth
Cell Adhesion Mediated By Integrin
Endothelial Cell Chemotaxis
Type B Pancreatic Cell Proliferation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Notch Signaling Pathway
Positive Regulation Of Ossification
Negative Regulation Of Insulin Secretion
Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Regulation Of Developmental Process
Cell Chemotaxis
Negative Regulation Of SMAD Protein Signal Transduction
Hematopoietic Stem Cell Homeostasis
Endothelial Cell-cell Adhesion
Negative Regulation Of Monocyte Chemotaxis
Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Negative Regulation Of Chondrocyte Proliferation
Negative Regulation Of Sensory Perception Of Pain
Bone Regeneration
Pathways
Drugs
Insulin human
Diseases
GWAS
Interacting Genes
31 interacting genes:
ADSL
ANKRD11
APOL6
C11orf87
CCN2
CDKN1A
COL8A1
DLL1
FAM90A1
FBLN1
FN1
FRS3
FXR1
FXR2
GJA1
HOXA1
IGF1
IGF2
INS
ITGAV
KRTAP5-6
LCE1A
LCE3D
NID2
NOTCH1
POLR2L
POU4F2
RECK
S100A4
TNIP3
ZNF330
Entrez ID
4856
HPRD ID
01291
Ensembl ID
ENSG00000136999
Uniprot IDs
P48745
PDB IDs
Enriched GO Terms of Interacting Partners
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Tissue Development
Epidermis Development
Integrin Binding
Positive Regulation Of Growth
Positive Regulation Of Developmental Growth
Regulation Of Growth
Regulation Of Developmental Growth
Regulation Of Cell Differentiation
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Fibroblast Proliferation
Receptor Ligand Activity
Insulin-like Growth Factor Receptor Binding
Positive Regulation Of Glycogen Biosynthetic Process
Wound Healing
Positive Regulation Of Signal Transduction
Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate
Regulation Of Cell Development
Regulation Of Nervous System Development
Insulin Receptor Binding
Positive Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Positive Regulation Of Developmental Process
Regulation Of Multicellular Organismal Process
Negative Regulation Of Gene Expression
Angiogenesis
Positive Regulation Of Cell Differentiation
Alphav-beta3 Integrin-IGF-1-IGF1R Complex
Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Negative Regulation Of Inner Ear Receptor Cell Differentiation
Compartment Pattern Specification
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Fibroblast Proliferation
Regulation Of Glycogen Biosynthetic Process
Basement Membrane
Negative Regulation Of Multicellular Organismal Process
Regulation Of Developmental Process
Response To Wounding
Extracellular Region
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Integrin-mediated Signaling Pathway
Positive Regulation Of Skeletal Muscle Tissue Growth
Endodermal Cell Differentiation
Positive Regulation Of D-glucose Import
Cell-matrix Adhesion
Regulation Of Neurogenesis
Regulation Of Glycogen Metabolic Process
Regulation Of Somitogenesis
Positive Regulation Of Neurogenesis
Regulation Of Skeletal Muscle Tissue Growth
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