NME2 and NME3

Number of citations of the paper that reports this interaction (PubMedID 11042679)
0

Data Source:
HPRD (in vivo)

		NME2	NME3
Description		NME/NM23 nucleoside diphosphate kinase 2	NME/NM23 nucleoside diphosphate kinase 3
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleus Cytoplasm Cytosol Focal Adhesion Lamellipodium Secretory Granule Lumen Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery Ficolin-1-rich Granule Lumen	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Cytoskeleton Membrane Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding DNA-binding Transcription Activator Activity DNA Binding Nuclease Activity Nucleoside Diphosphate Kinase Activity Protein Histidine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity GDP Binding Identical Protein Binding Metal Ion Binding G-quadruplex DNA Binding	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity GDP Binding CAMP Binding ADP Binding Metal Ion Binding Phosphatidic Acid Binding Mitochondrion-mitochondrion Outer Membrane Tether Activity
	Biological Process	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Cell Adhesion Integrin-mediated Signaling Pathway Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Keratinocyte Differentiation Regulation Of Epidermis Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II ITP Biosynthetic Process Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of DNA-templated Transcription Initiation	GTP Biosynthetic Process UTP Biosynthetic Process DTTP Biosynthetic Process CTP Biosynthetic Process DNA Repair Apoptotic Process Mitochondrial Fusion Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Protein Hexamerization Mitochondrial Outer Membrane Fusion
Pathways		Interconversion of nucleotide di- and triphosphates Neutrophil degranulation Azathioprine ADME Ribavirin ADME	Interconversion of nucleotide di- and triphosphates
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Height ( 20881960)
Interacting Genes		18 interacting genes: BNIPL CEBPA CTBP1 DNM1 GIT2 HERC3 HERC5 HERC6 MOB4 NME3 PPP2CA RAB5A RORA RORB SVIL TBXA2R TERF1 VIM	13 interacting genes: APP DESI1 FXR1 FXR2 HTR2A JAM2 NME1 NME2 SGTA SGTB UBQLN1 UBQLN2 UBQLN4
Entrez ID		4831	4832
HPRD ID		01132	03488
Ensembl ID		ENSG00000243678	ENSG00000103024
Uniprot IDs		F6XY72 P22392 Q6FHN3	Q13232
PDB IDs		1NSK 1NUE 3BBB 3BBC 3BBF 7KPF 8PIE 8PYW	1ZS6 8QVY 8QVZ 8QW0 8QW1 8QW2 8QW3
Enriched GO Terms of Interacting Partners?		White Fat Cell Differentiation Regulation Of Vesicle Size GDP Binding FAR/SIN/STRIPAK Complex Synaptic Vesicle Recycling Response To Lipid RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Integrated Stress Response Signaling Transcription Coregulator Binding Clathrin Coat Assembly Involved In Endocytosis Mitochondrial Outer Membrane Fusion Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Thromboxane Receptor Activity Thromboxane A2 Signaling Pathway Thromboxane A2 Receptor Activity Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Transcription Corepressor Binding Cellular Response To Lipid Nuclear Receptor Activity	Identical Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress ITP Biosynthetic Process Protein Histidine Kinase Activity TRC Complex Regulation Of ERAD Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Protein Metabolic Process ITP Metabolic Process Polyubiquitin Modification-dependent Protein Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Presynapse Regulation Of Cellular Response To Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Autophagosome Negative Regulation Of Long-term Synaptic Potentiation CTP Biosynthetic Process CTP Metabolic Process Regulation Of Primary Metabolic Process ERAD Pathway Nucleoside Diphosphate Kinase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Translation Regulator Activity Perinuclear Region Of Cytoplasm GTP Metabolic Process Positive Regulation Of Glycolytic Process Pyrimidine Ribonucleotide Biosynthetic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Dentate Gyrus Development Protein Targeting To ER Pyrimidine Nucleotide Biosynthetic Process Cytoplasmic Vesicle Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?