NFRKB and EPHB3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NFRKB	EPHB3
Gene Name		nuclear factor related to kappaB binding protein	EPH receptor B3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Ino80 Complex	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Dendrite
	Molecular Function	Protease Binding DNA Binding Protein Binding	Ephrin Receptor Activity ATP Binding Axon Guidance Receptor Activity
	Biological Process	DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Inflammatory Response	Angiogenesis Urogenital System Development Axon Guidance Axonal Fasciculation Cell Migration Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Regulation Of Rac GTPase Activity Substrate Adhesion-dependent Cell Spreading Regulation Of Cdc42 GTPase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Thymus Development Digestive Tract Morphogenesis Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Palate Development Dendritic Spine Development Dendritic Spine Morphogenesis
Pathways			EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: EPHB3 NFKB1 TRDMT1 UCHL5	9 interactors: CRK EFNB3 FYN GBE1 LNX1 MLLT4 NFRKB RASA1 RYK
Entrez ID		4798	2049
HPRD ID		01240	03502
Ensembl ID		ENSG00000170322	ENSG00000182580
Uniprot IDs		Q6P4R8	P54753
PDB IDs		3U21	3P1I
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-12 Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Vitamin D Biosynthetic Process Telencephalon Development C-5 Methylation Of Cytosine Positive Regulation Of MiRNA Metabolic Process Cellular Response To Nicotine Regulation Of Calcidiol 1-monooxygenase Activity Negative Regulation Of Cholesterol Transport Regulation Of MiRNA Metabolic Process Forebrain Development DNA Methylation On Cytosine Negative Regulation Of Monooxygenase Activity Dendritic Spine Morphogenesis Regulation Of Vitamin Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Membrane Protein Intracellular Domain Proteolysis Corpus Callosum Development Dendritic Spine Development Negative Regulation Of Interleukin-12 Production Cellular Response To Growth Factor Stimulus Response To Copper Ion Retinal Ganglion Cell Axon Guidance Dendritic Spine Organization Response To Growth Factor Forebrain Morphogenesis Regulation Of Catalytic Activity Negative Regulation Of Steroid Biosynthetic Process Regulation Of Rac GTPase Activity Negative Regulation Of Lipid Transport TRNA Methylation Lateral Ventricle Development Axonal Fasciculation Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Oxidoreductase Activity Cellular Response To Interleukin-6 Response To Organic Substance Regulation Of Cdc42 GTPase Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cdc42 Protein Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Response To Interleukin-6 Positive Regulation Of Synapse Assembly Positive Regulation Of Lipid Storage Membrane Protein Proteolysis Response To Amphetamine Regulation Of Signal Transduction Brain Development	Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Cell Development Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Regulation Of Ras GTPase Activity Regulation Of Cell Shape Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Ras Protein Signal Transduction Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Generation Of Neurons Regulation Of Signal Transduction Neurogenesis Regulation Of Small GTPase Mediated Signal Transduction Platelet Activation Negative Regulation Of Neuron Death Axon Choice Point Recognition Establishment Of Endothelial Intestinal Barrier Regulation Of GTPase Activity Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Signaling Neurotrophin Signaling Pathway Cell Surface Receptor Signaling Pathway Response To External Stimulus Regulation Of Neuron Apoptotic Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Phagocytosis Cellular Response To Platelet-derived Growth Factor Stimulus
Tagcloud ?			ascl2 cdh1 collapse compete corepressor crc demethylase deregulates disabling displaying emt encapsulation engages hdacs incompletely inducers intriguingly invasiveness lsd1 migratory palisading repress roadblock snail1 snail2 stemness tcf7l2 xenotransplants zeb1
Tagcloud (Difference) ?			ascl2 cdh1 collapse compete corepressor crc demethylase deregulates disabling displaying emt encapsulation engages hdacs incompletely inducers intriguingly invasiveness lsd1 migratory palisading repress roadblock snail1 snail2 stemness tcf7l2 xenotransplants zeb1
Tagcloud (Intersection) ?