SEPT2 and SEPT9

Number of citations of the paper that reports this interaction (PMID 12388755)
63

Data Source:
HPRD (in vivo)

		SEPT2	SEPT9
Gene Name		septin 2	septin 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Cell Cortex Actin Cytoskeleton Midbody Cleavage Furrow Ciliary Transition Zone Synapse Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Vesicular Exosome	Stress Fiber Cytoplasm Microtubule Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding GTP Binding Enzyme Regulator Activity Protein Complex Scaffold	GTPase Activity Protein Binding GTP Binding
	Biological Process	Regulation Of L-glutamate Transport Mitotic Nuclear Division Smoothened Signaling Pathway Neuron Projection Development Regulation Of Protein Localization Cilium Assembly Regulation Of Catalytic Activity Cell Division	Cell Cycle Metabolic Process Protein Heterooligomerization Cell Division
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Height ( 20881960)	Airflow obstruction ( 22837378) Body mass index ( 20966902)
Protein-Protein Interactions		13 interactors: COG4 CSNK2A1 DAZAP2 HN1L MTOR PIK3R2 PLEKHF2 S100A4 SEPT5 SEPT6 SEPT9 STMN1 STX1A	10 interactors: APP HIF1A HNRNPD IKBKG NEDD4 RAB10 SEPT11 SEPT2 SEPT6 SEPT7
Entrez ID		4735	10801
HPRD ID		03297	10360
Ensembl ID		ENSG00000168385	ENSG00000184640
Uniprot IDs		B5MCX3 Q15019	Q9UHD8
PDB IDs		2QA5 2QAG 2QNR
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Transport Cell Cycle Synaptic Vesicle Exocytosis Regulation Of Protein Complex Assembly Regulation Of Neurotransmitter Secretion Regulation Of Carbohydrate Utilization Golgi Vesicle Prefusion Complex Stabilization Regulation Of Transcription Factor Import Into Nucleus Cell Division Regulation Of Cellular Localization Cell Cycle Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Autophagy Cytokinesis Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Signaling Phosphatidylinositol-mediated Signaling Regulation Of Neurotransmitter Levels Insulin Receptor Signaling Pathway Regulation Of Exocytosis Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Transport ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Neurotransmitter Transport Regulation Of Protein Import Into Nucleus Vesicle-mediated Transport Regulation Of Establishment Of Protein Localization Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Negative Regulation Of NFAT Protein Import Into Nucleus Synaptic Vesicle Targeting Regulation Of Protein Localization To Nucleus Cell Morphogenesis Involved In Differentiation Establishment Of Vesicle Localization Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Regulation Of Nucleocytoplasmic Transport Vesicle Localization Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Neurotrophin Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase III Promoter Microtubule Depolymerization Fc-epsilon Receptor Signaling Pathway Regulation Of Protein Localization Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Macroautophagy	Cell Division Cell Morphogenesis Neuron Differentiation Cell Projection Organization Intracellular Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway B Cell Homeostasis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Anatomical Structure Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Axon Cargo Transport Neuromuscular Junction Development Generation Of Neurons Neuron Projection Development Regulation Of DNA-templated Transcription In Response To Stress Cell Projection Morphogenesis Cell Part Morphogenesis Visual Learning Outflow Tract Morphogenesis Neurogenesis Response To Light Stimulus Visual Behavior Lymphocyte Homeostasis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Neural Fold Elevation Formation Transmission Of Virus Basolateral Protein Localization Development Involved In Symbiotic Interaction Neuron Development Cell Development Associative Learning Leukocyte Homeostasis Regulation Of Synapse Structure Or Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Radiation Establishment Of Localization In Cell Synaptic Growth At Neuromuscular Junction Elastin Metabolic Process Regulation Of Embryonic Cell Shape Cytokinesis Immune System Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Establishment Of Neuroblast Polarity Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Collateral Sprouting In Absence Of Injury Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Viral Process Nervous System Development
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