NAP1L1 and MTIF2

		NAP1L1	MTIF2
Description		nucleosome assembly protein 1 like 1	mitochondrial translational initiation factor 2
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GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Membrane Melanosome	Nucleoplasm Cytoplasm Mitochondrion Intracellular Organelle Lumen
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Histone Binding Histone Chaperone Activity	Nucleotide Binding RNA Binding Translation Initiation Factor Activity GTPase Activity GTP Binding Translation Factor Activity, RNA Binding Ribosomal Small Subunit Binding
	Biological Process	DNA Replication Nucleosome Assembly Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation	Translation Translational Initiation Regulation Of Translational Initiation Ribosome Disassembly Mitochondrial Translational Initiation
Pathways			Mitochondrial translation initiation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341)
Interacting Genes		34 interacting genes: ANKRD23 C1QTNF9 CHORDC1 CREBBP CSNK2A1 CSNK2B DLST DYRK1A EP300 ERCC6 FSD1 GAS2L2 H1-1 H4C1 HBA1 HMGB2 HSPB1 ISG15 LINC01554 MED10 MTNR1A NAP1L2 NR2F6 OGT POT1 RPL23 RPL23A RPS15 SNCA SP1 SUMO2 TERF1 TP53 TPX2	4 interacting genes: HSPB1 NFKBIB TSC22D2 UBASH3A
Entrez ID		4673	4528
HPRD ID		01248	04792
Ensembl ID		ENSG00000187109	ENSG00000085760
Uniprot IDs		B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0	P46199 Q6P1N2
PDB IDs		7BP5 7UN3 7UN6	6GAW 6GAZ 6GB2 6RW5 7PO2 8QRN
Enriched GO Terms of Interacting Partners?		Rhythmic Process Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Nucleoplasm Negative Regulation Of DNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Cellular Response To Heat Transcription Coactivator Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Tau Protein Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H3K18 Acetyltransferase Activity Double-strand Break Repair N-terminal Peptidyl-lysine Acetylation Chromatin Remodeling Cellular Component Assembly Peptide Lactyltransferase (CoA-dependent) Activity Chromatin Organization Regulation Of Cellular Component Organization Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Double-strand Break Repair Via Nonhomologous End Joining Symbiont-mediated Disruption Of Host Cell PML Body Circadian Rhythm Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Actinomycin D Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Histone Acetyltransferase Complex Negative Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Microtubule-based Process Response To Actinomycin D Regulation Of Primary Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Amide Metabolic Process Regulation Of Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromatin DNA Binding Regulation Of Protein-containing Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of G1 To G0 Transition
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