ZMYND11 and MAGEC2

Number of citations of the paper that reports this interaction (PubMedID 24866244)
0

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		ZMYND11	MAGEC2
Description		zinc finger MYND-type containing 11	MAGE family member C2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K36me3 Reader Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Chromatin Organization Regulation Of Signal Transduction Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Non-response to bupropion and depression ( 27622933)
Interacting Genes		26 interacting genes: ARHGEF18 BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 H4C1 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1	15 interacting genes: MDM2 MNAT1 P4HA3 PBX3 PCGF6 RBX1 RNF166 SSX1 SSX2 TAF9 TRAF4 TRIM28 TRIM8 UBR3 ZMYND11
Entrez ID		10771	51438
HPRD ID		09830	06632
Ensembl ID		ENSG00000015171	ENSG00000046774
Uniprot IDs		A0A0D9SGD6 A0A994J4C0 A0A994J4I8 A0A994J6Y5 B7Z2J6 E7ENI9 Q15326 Q5BJG6 Q5UGI2	Q9UBF1
PDB IDs		4NS5 5HDA
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Endoderm Development Regulation Of MiRNA Metabolic Process Chromatin Organization Negative Regulation Of Metabolic Process Subtelomeric Heterochromatin Formation Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Positive Regulation Of MiRNA Transcription Constitutive Heterochromatin Formation Chordate Embryonic Development Heterochromatin Formation Negative Regulation Of Androgen Receptor Signaling Pathway Cell Differentiation Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of MiRNA Metabolic Process Multicellular Organism Development Positive Regulation Of Transforming Growth Factor Beta Production RNA Polymerase II Core Promoter Sequence-specific DNA Binding Cellular Developmental Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cell Differentiation Histone H3K27 Trimethyltransferase Activity Paraxial Mesoderm Morphogenesis Chromosome, Telomeric Region RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Animal Organ Morphogenesis Positive Regulation Of Macromolecule Metabolic Process	Zinc Ion Binding Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Regulation Of Primary Metabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription Modification-dependent Protein Catabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Proteasomal Protein Catabolic Process Post-translational Protein Modification Regulation Of Metabolic Process Ubiquitin-protein Transferase Activity Protein Polyubiquitination Suppression Of Viral Release By Host Ubiquitin Protein Ligase Binding SUMO Transferase Activity Protein Ubiquitination Protein Catabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Macromolecule Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Gene Expression Respiratory Gaseous Exchange By Respiratory System Proteolysis Transferase Activity Regulation Of Macromolecule Biosynthetic Process Response To Stress DNA Damage Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Transcription Corepressor Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Apoptotic Process
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