MUC7 and SELL

Number of citations of the paper that reports this interaction (PubMedID 9538010)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		MUC7	SELL
Description		mucin 7, secreted	selectin L
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Golgi Lumen Plasma Membrane Extracellular Exosome	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Membrane Secretory Granule Membrane
	Molecular Function	Protein Binding	Protease Binding Calcium Ion Binding Protein Binding Heparin Binding Carbohydrate Binding Sialic Acid Binding Glycosphingolipid Binding Metal Ion Binding Oligosaccharide Binding
	Biological Process	Killing Of Cells Of Another Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Cytokine Leukocyte Migration Leukocyte Tethering Or Rolling Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Defective GALNT3 causes HFTC Defective C1GALT1C1 causes TNPS Defective GALNT12 causes CRCS1 Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Diabetic nephropathy in type 1 diabetes ( 31537649)	Acne (severe) ( 24399259) Amyotrophic lateral sclerosis ( 19451621) Basophil percentage of white cells ( 32888494) Blood protein levels ( 30072576) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479) Monocyte count ( 32888494)
Interacting Genes		8 interacting genes: AMY1A GALNT10 GALNT12 GALNT14 HTN3 LTF PCGF1 SELL	16 interacting genes: CD4 CFH EMCN EZR GRB2 MSN MUC7 PODXL PODXL2 PRKCA PRKCQ PRKG1 SELE SELPLG SLC30A2 VCAN
Entrez ID		4589	6402
HPRD ID		11759	07034
Ensembl ID		ENSG00000171195	ENSG00000188404
Uniprot IDs		Q8TAX7	P14151
PDB IDs			2LGF 3CFW 5VC1
Enriched GO Terms of Interacting Partners?		Polypeptide N-acetylgalactosaminyltransferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Carbohydrate Binding Metal Ion Binding Protein O-linked Glycosylation Protein Glycosylation Macromolecule Glycosylation Glycosylation Glycosyltransferase Activity Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Defense Response To Fungus Response To Fungus Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Alpha-amylase Activity Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Carbohydrate Derivative Biosynthetic Process Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Killing Of Cells Of Another Organism Positive Regulation Of Bone Mineralization Involved In Bone Maturation Phagocytic Vesicle Lumen Membrane Destabilizing Activity Antimicrobial Humoral Response Heparin Binding Negative Regulation Of Osteoclast Development Golgi Membrane Extracellular Space Glycosphingolipid Binding Cell Killing Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development Carbohydrate Derivative Metabolic Process Cytolysis By Host Of Symbiont Cells Antifungal Humoral Response Chloride Ion Binding Humoral Immune Response Negative Regulation Of ATP-dependent Activity Negative Regulation Of Membrane Potential Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Osteoblast Proliferation Oligosaccharide Binding Specific Granule Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cation Binding Host-mediated Suppression Of Viral Proces Defense Response To Bacterium	Leukocyte Cell-cell Adhesion Cell Adhesion Regulation Of Cell-cell Adhesion Uropod Plasma Membrane Leukocyte Tethering Or Rolling Leukocyte Adhesion To Vascular Endothelial Cell Microvillus Membrane Regulation Of Platelet Aggregation Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Cell Migration Membrane To Membrane Docking Positive Regulation Of Cell-cell Adhesion Regulation Of Platelet Activation Cell Motility Regulation Of Interleukin-2 Production Positive Regulation Of Early Endosome To Late Endosome Transport Microvillus Regulation Of Immune System Process Positive Regulation Of Protein Localization To Early Endosome Filopodium Positive Regulation Of Protein Localization To Endosome Cell-cell Adhesion Positive Regulation Of Leukocyte Cell-cell Adhesion Immune System Process Golgi Lumen Establishment Of Epithelial Cell Apical/basal Polarity Diacylglycerol-dependent Serine/threonine Kinase Activity Leukocyte Activation Regulation Of Early Endosome To Late Endosome Transport T Cell Activation Establishment Of Apical/basal Cell Polarity Positive Regulation Of Immune System Process Regulation Of Cell Activation Glycosaminoglycan Binding Epithelial Cell Development Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Cell Activation Cortical Cytoskeleton Gland Morphogenesis Establishment Of Epithelial Cell Polarity Regulation Of Leukocyte Cell-cell Adhesion Signaling Receptor Binding Actin Filament-based Process Plasma Membrane Raft Positive Regulation Of Interleukin-2 Production Establishment Of Endothelial Barrier
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