MTAP and CENPH

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTAP	CENPH
Gene Name		methylthioadenosine phosphorylase	centromere protein H
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol
	Molecular Function	Phosphorylase Activity S-methyl-5-thioadenosine Phosphorylase Activity	Protein Binding Kinetochore Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Purine Ribonucleoside Salvage Polyamine Metabolic Process Nicotinamide Riboside Catabolic Process L-methionine Biosynthetic Process From Methylthioadenosine Methylation Response To Testosterone Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process	Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization
Pathways		Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives	Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs		Adenine (1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol Formycin 5\'-Deoxy-5\'-Methylthioadenosine 5\'-Deoxy-5\'-(Methylthio)-Tubercidin
Diseases
GWAS		Coronary heart disease ( 21606135) Cutaneous nevi ( 19578365) Melanoma ( 21983787)
Protein-Protein Interactions		6 interactors: CDC25A CENPH FOLH1 LYRM1 MYLIP RELB	5 interactors: CENPK KIF2C MTAP NDC80 NUF2
Entrez ID		4507	64946
HPRD ID		01134	12029
Ensembl ID		ENSG00000099810	ENSG00000153044
Uniprot IDs		B4DUC8 Q13126	B3KVZ3 Q9H3R5
PDB IDs		1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE
Enriched GO Terms of Interacting Partners?			Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Cycle Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Mitotic Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Chromosome Organization Cell Cycle Process Attachment Of Mitotic Spindle Microtubules To Kinetochore Purine Ribonucleoside Salvage Organelle Organization L-methionine Biosynthetic Process From Methylthioadenosine Establishment Of Organelle Localization Microtubule Depolymerization L-methionine Salvage Attachment Of Spindle Microtubules To Kinetochore Organelle Localization Microtubule Cytoskeleton Organization Methionine Biosynthetic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Purine-containing Compound Salvage CENP-A Containing Nucleosome Assembly Mitotic Metaphase Plate Congression Polyamine Metabolic Process Metaphase Plate Congression Histone Exchange DNA Replication-independent Nucleosome Assembly Response To Testosterone Establishment Of Mitotic Spindle Orientation Microtubule Polymerization Or Depolymerization Mitotic Spindle Organization Sulfur Amino Acid Metabolic Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Chromosome Localization Microtubule-based Process Centromere Complex Assembly Spindle Localization Microtubule Anchoring ATP-dependent Chromatin Remodeling Regulation Of Chromosome Segregation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Tagcloud ?		9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts	angptl2 bik blast blasts candidate causative commercial cytopenia dysplasia epigenetic excess focusing gstm5 hypermethylation mapped methylated methylation modalities multilineage networks pairs preleukemic promoters raeb rcmd refractory rerg silencing transforms
Tagcloud (Difference) ?		9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts	angptl2 bik blast blasts candidate causative commercial cytopenia dysplasia epigenetic excess focusing gstm5 hypermethylation mapped methylated methylation modalities multilineage networks pairs preleukemic promoters raeb rcmd refractory rerg silencing transforms
Tagcloud (Intersection) ?